To see why, consider the following model. Take two log-linear plots, one for cost per unit of compute power (CPU cycles, disk space, RAM, what have you), and one for cost per unit of sequence ($$ per bp of DNA). Now suppose that sequence cost is decreasing faster than compute cost, so you have two nice, diverging linear lines when you plot these trends over time on a log-linear plot (see Figure 2).
It's also worth noting that de novo assembly (my current focus...) remains one of the biggest challenges. It requires gobs of the most expensive computational resource (RAM, which is not scaling as fast as disk and CPU), and there are no good solutions on the horizon for making it scale faster. Neither mRNAseq nor metagenomics are well-bounded problems (you always want more sequence!), and assembly will remain a critical approach for many people for many years. Moreover, cloud assembly approaches like Contrail are (sooner or later) doomed by the same logic as above.
□ ctitusbrown: 次世代シーケシング戦略の議論において重要な三つのコンポーネント。商業的弊害/アセンブラ/ゲノム自体の反復構造
Assembling genomes with modern sequencing (blog post) ivory.idyll.org/blog/aug-11/as… #bioinformatics
A key component of any sequencing strategy discussion nowadays is that sequencing has become very commercial.While this drives down costs (pretty dramatically!), you also can't trust a damn thing that sequencing companies say, because the market is very competitive and there's very little percentage in straight-up honesty, much less full disclosure.
□ articlescouk: バイオインフォマティクス市場の巨大な成長。アプリケーションの需要拡大により2013年までに62億ドル市場に。データベース分野ではDDBJなどの日本がリードする機能強化の寄与も。
Global Bioinformatics Market to Witness Stupendous Growth http://goo.gl/fb/bVWs7
We have found that Japan has effectively strengthened its capabilities to be a worldwide player in the field of bioinformatics databases. With an estimated revenue of Yen 38 Billion (US$ 0.46 Billion) in 2010, the market is likely to attract more players in the years to come. The country has one of the largest databases for bioinformatics across the globe known as DDBJ, in comparison to USA (GenBank) and Europe (EMBL-Bank).
□ BlowtheMind:
Is Electronic Music 'Real Music?' RL talks to Songify-creator Parag Chordia (@indianmusic) and IDM artist @RichardDevine http://is.gd/q72Exe
□ この記事はマジで必見。DiscoveryNewsのRichard Devineへのインタビュー。アルゴリズム作曲とソフトウェア、Autechreにも言及してます / The Alien Sounds of Richard Devine : http://t.co/VSVHUHA
□ cdmblogs:
Music: Not a Turntable, Not a Knob - A New Inertial Sensor Music Controller, as Artists Explore http://cdm.fm/qF6aCY
円盤状の慣性センサーを利用した、全く新しい概念の音響ツール。今までは複雑なアルゴリズムを要したエフェクトも、どんどん物理化・可触化して行くのかも
□ DivaBiotech:
Spotlight on Nigeria, Kenya, Ghana - Africa's vast new tech opportunity (Wired UK): bit.ly/os2YLv
□ OA_Africa: Open Access Africa
@BiomedCentral are bringing #OpenAccess #Africa #publishing initiative to West Africa http://ow.ly/5VfOP #opendata #openscience #OA
□ DailyNewsGW:
Pronto Diagnostics to Distribute Vermillion's OVA Test in Israel, Palestinian Territories: Pronto will begin off... http://bit.ly/roW8Yh
□ ongenetics: Steve Mount
All 4096 hexamers evaluated for their effect on splicing (when placed in an internal exon). Ke et al. @GenomeResearch bit.ly/GeneNews
□ rnomics:
Biogenic mechanisms and utilization of small #RNAs derived from human protein-coding genes: The nature... http://bit.ly/nq9J5F #nature
□ rnomics:
Merck Shuts Down RNAi Research Center in SF Cutting 50 Jobs: Merck has decided to close down the... http://bit.ly/nyBwjd #bioportfolio
□ Xconomy:
Merck shuts down RNAi center in SF, the fmr Sirna Therapeutics. A late-breaker from last Fri pm http://bit.ly/mUtfdK
□ IPTVeducation:
Check out "Science Bytes"-series of short videos, based on studies from @PLoS, highlighting science discoveries http://bit.ly/qVXrUx #STEM
□ chilhalprit:
New Products: The Malaysian Genomics Resource Center Berhad has updated its free online bioinformatics analysis ... http://bit.ly/nUSIBr
□ dgmacarthur:
Very interesting. RT @bachinsky: Assumptions, not data, dictate opinions about predictive genetic testing in youth: bit.ly/pzc4B4
□ BerkeleyLabTABL:
Lab Scientist to Direct Bioinformatics at CREA: Steve Garan, a long-time guest scientist at the Physical Bioscie... http://bit.ly/oLtDaF
□ RainDanceTech:
Genome Research and PLoS ONE publish studies from Scripps & Christian-Albrechts validating RainDance’s MethylSeq: goo.gl/ZqGGm
□ CellPressNews:
Today we launched Cell Reports, our first all open-access journal. Find out more and submit your papers here http://ow.ly/5SpQx #science
□ PLoS:
Keep those great #binarybattle app ideas coming! We at @PLoS and @mendeley_com love what's been shared so far! mendeley.com/blog/developer…
The annual international conference on Intelligent Systems for Molecular Biology (ISMB) is the major meeting of the International Society for Computational Biology (ISCB). Over the past eighteen years the ISMB conference has grown to become the world’s largest bioinformatics/computational biology conference, and ISMB/ECCB 2011 will be the year’s most important computational biology event globally.
□ VIZBI 2011: NIH conference on visualizing biological data
As biological data grows rapidly in volume and complexity, biologists rely increasingly on computational visualization to gain insight from data. The VIZBI 2011 conference brought together researchers developing and using computational tools to visualize data from genomes, transcripts, proteins, cells, organisms, and populations. VIZBI 2011 was held March 16-18 at the Broad Institute, Cambridge MA, USA.
□ kiharalab:
Kihara, Juan Rodriguez, Meghana Chitale will head to ISMB at Vienna http://bit.ly/g51K5l tomorrow. Attend 3D-SIG, AFP/CAFA, main conf. #ismb
Two initiatives to promote data sharing held workshops at the conference: BioSharing and ELIXIR. At the BioSharing workshop, which discussed the bioDBcore database cataloging project, Genome Biology appeared on the panel as a voice of open access publishing and representative of BioMed Central. In addition to Genome Biology, BioMed Central had several other journals represented at the ISMB, including a strong presence from BMC Bioinformatics and GigaScience.
□ bioontology: NCBO
NCBO Web Services and Development of Semantic Applications, bit.ly/nALNgS #ismb
Despite the advantages of using the enormous user base, the drawback of using a wikipedia based system is the lack of semantic representation. Using semantic media wiki to combine this externally may solve some of this issue, and Ben Good followed this talk showing how genes can be linked to diseases by making a wiki mashup of SNPedia with Gene Wiki.
WikiProject Computational Biology is aimed at improving and organising articles on Computational Biology, Bioinformatics, Computational Systems Biology and related topics.
□ YabiProject: A more complex workflow in Yabi that demonstrates running tasks in parallel.
Almost time for our #ISMB tech talk. New movie of Yabi using @emblebi web services youtu.be/zLCNAqn8nFE?hd…
□ F1000: I still haven’t found what I’m looking for
Sciencenet -- a multidimensional search engine http://bit.ly/nS6xTd
There is a prototype at http://sciencenet.kit.edu/. I’ve had a little play, and think I’m going to put the emphasis on prototype. I ran a search on a protein close to my heart and found the results not quite as useful as if I’d gone directly to some of the more familiar databases. Perhaps Sciencenet will improve with time?I certainly hope so?or maybe we should think about a filtering mechanism on top of this search engine (hey, now that sounds familiar).
Biology Open is an online-only Open Access journal that publishes original research across all aspects of biological science, including cell science, developmental biology and experimental biology. Biology Open aims to provide rapid peer-reviewed publication for good-quality scientifically sound observations in these allied fields.
□ micheldumontier:
#dlab Check out our PLOS One paper on semantic interoperability using relation expansion: plosone.org/article/info%3…
Interoperability between Biomedical Ontologies through Relation Expansion, Upper-Level Ontologies and Automatic Reasoning.
We describe a method to improve automated reasoning over biomedical ontologies and identify several thousand contradictory class definitions. Our approach aligns terms in biomedical ontologies with foundational classes in a top-level ontology and formalizes composite relations as class expressions.
□ DailyNewsGW:
LaserGen, National Instruments to Collaborate on Next-gen Sequencing System: The firms aim to have a system deve... http://bit.ly/piarUN
□ BioMedCentral:
‘Beyond the Tree of Life’: a new thematic series from #BiologyDirect http://ow.ly/5DbpX #biology #evolution
The Tree of Life is a powerfully attractive representation of an evolutionary process and pattern that has been severely challenged by the discovery of extensive horizontal gene transfer in bacteria, archaea and other organisms.
□ DailyNewsGW: GenomeWeb News
Coriell Using IBM for Biosample Management: read more http://bit.ly/nuhmVW
□ ReaderMeter: Dario Taraborelli
Wikimedia joining forces with open science: bit.ly/nV03IT #OA #opendata //cc: @PLoS @sciencecommons
□ celldna: Cell DNA
New Virus Jumps From Monkeys to Lab Worker - Study shows for the first time that an adenovirus can cross the species... http://ow.ly/1dPdDw
□ appliedgenomics:
Very interesting Harvard/MIT study turns the entire genome of a bacterium into an “editable and evolvable template": bit.ly/n3KVSc
□ rnomics: Fabrice Leclerc
Immunovirological and Biochemical Changes in Nigerian Patients with Hepatitis B Coinfection on... http://bit.ly/puzAgV #WWS
□ DivaBiotech: Ruby Gadelrab
Africans are seriously underrepresented in GWAS! Genome Revolution Is Skipping Non-Whites | Wired Science | Wired.com bit.ly/rqxJlv
□ DivaBiotec:
Spotlight on Nigeria, Kenya, Ghana - Africa's vast new tech opportunity (Wired UK): bit.ly/os2YLv
□ PLoSMedicine:
World’s first “home grown” African first-aid guidelines: http://bit.ly/qO8pa9
Evidence-Based African First Aid Guidelines and Training Materials
In sub-Saharan Africa, much disease and injury can be addressed by emergency care. First aid training has been promoted as an inexpensive way to save lives. However, first aid training in sub-Saharan Africa is often based on handbooks prepared outside of the continent that are not adapted to the African context.
We formulated evidence-based guidelines that comprehensively address how basic first responders should be trained to manage emergency situations in an African context. The guidelines focussed on first aid interventions requiring minimal or no equipment.
□ reliefweb:
New openaccess publication for disaster management research calls for papers bit.ly/qjXoWG @PLoS Currents: Disasters
□ MissouriCures: MissouriCures.org
#Stemcell treatment may improve functional learning and memory loss in #braincancer patients http://bit.ly/nra8lU #stemcells #cancer
By extending a cell-cycle model previously developed for embryos of the frog Xenopus laevis to include the spatial dimensions of the embryo, we establish a novel role for the rapid, fertilization-initiated calcium wave that triggers cell-cycle oscillations.
Specifically, in our simulations a fast calcium wave results in synchronized cell cycles, while a slow wave results in full-blown spatio-temporal chaos. We show that such chaos would ultimately lead to an unpredictable patchwork of cell divisions across the embryo. Given this potential for chaos, our results indicate a novel design principle whereby the fast calcium-wave trigger following embryo fertilization synchronizes cell divisions.
Recently, small-scale quantum communication has been realized by transporting entangled photons, rendering potentially feasible quantum networks on large scales. We propose a class of quantum networks comprising quantum repeaters for long-distance information transport and local networks of fibers and switches.
As the transmitting capability is limited by the node bandwidth, photon loss can occur through the dynamical process of cascading when the network is under external perturbations. We obtain results that can be used to guide quantum network design to minimize the photon loss.
□ OxfordJNLsJapan:
【生物学・植物】Plant Ecologyから無料アクセス論文：植物種が豊富なことが林分構造と生産性に与える影響について http://oxford.ly/q9Getw #plants
Effects of plant species richness on stand structure and productivity.
□ OxfordJNLsJapan:
【ライフサイエンス】魚類と哺乳類の噛み方の違いは顎と舌骨の形の違いhttp://bit.ly/jtfqrG 原著論文はこちらから http://oxford.ly/jVpFGH #fish #animals #mammals
Evolution of Muscle Activity Patterns Driving Motions of the Jaw and Hyoid during Chewing in Gnathostomes
□ Hypios:
Michael Bonner and Klaus-Peter Speidel debunk the myth that solutions are the only benefit of open... http://fb.me/DDPyOQEU
Sometimes the Solution is not the Solution.
If companies only focus on the solution, if they construe this as the only valuable thing that can come from Open Problem-Solving or Open Innovation, they will be disappointed if this solution does not come. Similarly, if a solution is found but discarded, the company will seem to have wasted its time and money. It is better to think of Open Innovation as a process of development or maturation within R&D: a fundamental cultural shift in a company’s approach to thinking about problems.
Biophilia is an extraordinary and innovative multimedia exploration of music, nature and technology by the musician Björk. Comprising a suite of original music and interactive, educational artworks and musical artifacts, Biophilia is released as ten in-app experiences that are accessed as you fly through a three-dimensional galaxy
01. The Rainmaker
02. Mother Africa
03. Of Death And Dying
04. Limpopo River Song (The Bulawayo Church Choir)
05. The Power Of One (Teddy Pendergrass)
06. Woza Mfana
07. Southland Concerto
08. Senzenina
09. Penny Whistle Song
10. The Funeral Song (The Bulawayo Church Choir)
11. Wangal Unozipho (The Bulawayo Church Choir)
12. Mother Africa Reprise
Original Score by Hans Zimmer
Arranged by Hans Zimmer and Lebo M.
Orchestrated by Bruce Fowler
Produced by Hans Zimmer, Lebo M. and Jay Rifkin
1930年代アパルトヘイト化の南アフリカを舞台に、一人の英国少年と現地人とのボクシングを通じた青春を描いた、Bryce Courtenayの小説"The Power Of One"の映画化に際して製作され、当時はシンセサイザー・スコアの名手として活躍していたハンス・ジマーが、アフリカの民族音楽を取り入れる新機軸となった叙事詩的サウンドトラック。
私にとってHans Zimmerと言えば、"Lion King"や"pirates of the caribbean"よりも真っ先に思い浮かぶのが、この作品。
実は"Lion King"にはもっと直接の前身的作品がある。1992年製作のPBSドキュメンタリー"Millennium: Tribal Wisdom And The Modern World"に提供した楽曲は、当時のジマーの最大のセールス（帯ではTangerine Dreamとの仕事が紹介されている）であったシンセ・ミュージックスタイルに、アフリカの民族音楽要素を散りばめた内容となっており、実はこの中の一部のメロディが、そっくり『ライオン・キング』に流用されている。
また、ジマーが同時期に手がけている幾つかの作品、とりわけ『愛と精霊の家 (The House of the Spirits)』などに代表される、叙事詩的映像に適性のある楽曲を得意としていたことも、人情の機微を繊細なタッチで音譜に写し取る天才であることも、90年代後半における男臭いアクション・スコアの巨匠としてのポジションの確立が、必然に他ならなかったことを物語っている。
The first single off the album, "Promises," is scheduled for release on Black Hole Recordings in June.
their second full-length album would have to wait. Much to their fans' relief, Mavie and Josh decided to reform as a duo, and the resulting full-length record is due for release in Winter 2011.
NEW Album "The Book Of Secrets" Coming Soon.
Mystico is a combination of 4 musical elements,
Gregorian Chants, Opera Chants, Piano and Electronic Rhythms.
8000 lanterns were released by Poznan in Poland June 21st, 2011 for the first day of summer. The 8000+ lanterns are a world record and the city plans on beating that record again next year.
<object height="81" width="100%"> <param name="movie" value="http://player.soundcloud.com/player.swf?url=http%3A%2F%2Fapi.soundcloud.com%2Ftracks%2F11360773"></param> <param name="allowscriptaccess" value="always"></param> <embed allowscriptaccess="always" height="81" src="http://player.soundcloud.com/player.swf?url=http%3A%2F%2Fapi.soundcloud.com%2Ftracks%2F11360773" type="application/x-shockwave-flash" width="100%"></embed> </object> Last Train - Kenneth Thomas Orange Room Remix by phosproject
□ Phos Project / "Last Train" Remixes
イタリアのElectro/Tech House DJのPhos Projectが、Banco De Gaiaの"Last Train To Lhasa"のカヴァーSingleをリリース。リミキサーにKenneth Thomasも起用されてます。冷たくて重厚なケネス節が鈍く光るこのリミックスが断然良い。
LONDON--For 80 years, Abbey Road Studios has been one of the most important places in the music business.
CNET got a chance to visit and see some of the most impressive studio rooms and equipment in the industry. Including a microphone that both McCartney and Lennon often sung into.
□ Science Tweets.
□ BSECS: 18th Century Studies
For free access to Abigail Williams’s new piece on Swift’s Journal to Stella see res.oxfordjournals.org/content/early/…
スウィフトの書簡集『ステラへの消息』のアビゲイル氏による解題
□ NatureJapan: 男性器のサイズと指の長さに関連性：
Second to fourth digit ratio: a predictor of adult penile length
Asian Jouranl of Andrology http://nature.asia/qMPQez
□ InsideScience: 細胞中のフラクタル構造解析を癌細胞テストに応用。 bit.ly/n9wY5z - Searching For Fractals May Help Cancer Cell Testing - Tool compares geometry of cells to find potentially cancer cells
Fractal geometry apparently also appears in the human body. The pattern of heartbeats over long intervals looks fractal. How about the geometry of cells? And could the observation of fractal geometry be used to identify cancer cells?
□ InsideScience: 第二次世界大戦中の爆撃の及ぼす地球気候学的影響 http://bit.ly/ruGG8c - Did WWII Bombing Raids Alter The Weather? - Data supports theory that contrails alter ground temps #climate #ISNS
On May 11, 1944, a warm and cloudless spring day, U.S. Army Air Force B-24 Liberators, B-17 Flying fortresses and their fighter escorts lifted off from airfields across southeast England. They climbed, circled, and then formed into one huge formation before heading out to bomb targets in Nazi-occupied Europe.
The bombers and hundreds of fighters flying escort, forming two missions four hours apart, filled the sky with contrails. Researchers from Lancaster University and the Environmental Agency in the U.K. combed through military and meteorological records and determined that the vast cloud cover created by aircraft condensation trails -- or contrails -- slowed the rise of temperatures on the ground that morning.
□ AIP_Publishing:
Social influencing and associated random walk models: Asymptotic consensus times on the complete graph http://ow.ly/5wSxX #AIP_CHAOS
We investigate consensus formation and the asymptotic consensus times in stylized individual- or agent-based models, in which global agreement is achieved through pairwise negotiations with or without a bias.
Considering a class of individual-based models on finite complete graphs, we introduce a coarse-graining approach (lumping microscopic variables into macrostates) to analyze the ordering dynamics in an associated random-walk framework.
□ AIP_Publishing: 現実に構築されるネットワークの低次数ノードの集団力学的影響。
Sample-to-sample fluctuations in real-network ensembles http://ow.ly/5zGe4 #AIP_CHAOS
Network modeling based on ensemble averages tacitly assumes that the networks meant to be modeled are typical in the ensemble. Previous research on network eigenvalues, which govern a range of dynamical phenomena, has shown that this is indeed the case for uncorrelated networks with minimum degree ??3.
Here, we focus on real networks, which generally have both structural correlations and low-degree nodes. We show that: (i) the ensemble distribution of the dynamically most important eigenvalues can be not only broad and far apart from the real eigenvalue but also highly structured, often with a multimodal rather than a bell-shaped form; (ii) these interesting properties are found to be due to low-degree nodes, mainly those with degree ??3, and network communities, which is a common form of structural correlation found in real networks.
In addition to having implications for ensemble-based approaches, this shows that low-degree nodes may have a stronger influence on collective dynamics than previously anticipated from the study of computer-generated networks.
ONE: Put People First TWO: Smaller Can Be Beautiful THREE: One Bad Operation Can Undo Ten Good Ones FOUR: Exploit Openings, Don’t Force Them FIVE: Trust Is Not Virtual
The largest digital camera ever built for a space mission has been painstakingly mosaicked together from 106 separate electronic detectors. The resulting "billion-pixel array" will serve as the super-sensitive 'eye' of ESA's Galaxy-mapping Gaia mission.
While the naked human eye can see several thousand stars on a clear night, Gaia will map a billion stars within our own Milky Way Galaxy and its neighbours over the course of its five-year mission from 2013, charting their brightness and spectral characteristics along with their three-dimensional positions and motions.
On 9 July the Republic of South Sudan becomes the earth's newest country - instantly making the world's atlases completely out of date. So here's your new guide to the globe to download and explore. Just click 'play' below and use Prezi's pan and zoom buttons by mousing over the right of the screen
□ MSF_USA: Doctors w/o Borders: 南スーダン独立に伴う緊急人道医療のMSFの応答。 健康予算・帰還民対応・疫病対策・産科ケア
An interview with MSF head of mission in South Sudan: "A massive humanitarian emergency." http://bit.ly/o5aJ9v#SouthSudan
In this humanitarian emergency, MSF will continue to provide essential medical aid where the needs are greatest, and where we can be of most relevance and benefit to the population. Improving access to healthcare and improving its emergency response has to be a priority for this new country.
However, the government of South Sudan has allocated just 3.7 percent of its budget to health in 2011, a decrease from 7.9 percent in 2006. It is essential that emergency humanitarian needs are adequately prioritized by the South Sudanese government, by donor governments and by international humanitarian NGOs.
□ Call for papers: International Journal of Public Research for special issue: 40 years of the spiral of silence http://oxford.ly/hJ03k8 (pdf)
It was in 1972 when Elisabeth Noelle-Neumann first outlined the main fea- tures of the theory of the spiral of silence at the 20th International Congress of Psychology in Tokyo. Forty years later, in the year 2012, the International Journal of Public Opinion Research is planning to publish a special edition of the Journal focusing on the theory. Guest editor is Dr. Thomas Petersen.
□ NatureNews: Almost everything that distinguishes the modern world from earlier centuries is attibutable to science. - Bertrand Russell
□ Biology.
□ oatp: OA Tracking Project
GigaScience, Giga-database and now GigaBlog: new resources for the big-data community: ""As biological data is n... http://bit.ly/ndlx5D
As biological data is now produced faster than it can easily be handled and stored, the dissemination of this data has become a major bottleneck. GigaScience: a new type of journal from BioMed Central and BGI ? no stranger to these issues being the world’s largest Genomics center ? starts taking submissions today with the goal of addressing many of the issues surrounding “big-data”.
□ rnomics: Fabrice Leclerc
Dynamics of a Plant RNA Virus Intracellular Accumulation: Stamping Machine vs. Geometric... http://bit.ly/rf6YMK #lifesciences
□ TriLinkBioTech:
Antisense Oligonucleotide Targeting Survivin Induces Apoptosis of Pancreatic Cancer Cells bit.ly/od1jQe
□ GENbio: 多能性前駆細胞から多能性ヒト造血幹細胞の分離を可能にするマーカーの特定
Scientists Identify Marker Enabling Segregation of True Human Hematopoietic Stem Cells from Multipotent Progenitors http://bit.ly/o6KBuj
Scientists claim to have identified markers that enable the segregation of rare, truly pluripotent human hematopoietic stem cells (HSCs) from multipotent progenitors (MPPS). They identified CD49f as a specific marker for pluripotent HSCs, enabling their isolation using flow cytometry.
□ freesci: Pawel Szczesny
Systems Biology Knowledgebase http://j.mp/qIZlVT Interesting, fully open (!), but level of funding unconvincing.
Washington, DC?The DOE Office of Science (SC) announced today the selection of a collaboration of top scientists from across the Nation to lead development of a computer-based Systems Biology Knowledgebase (http://genomicscience.energy.gov/compbio/index.shtml#page=news) for the scientific community that is designed to advance understanding of microbes and plants for energy and environmental solutions.
□ ewanbirney:
Ensembl uses the AWS cloud to move data closer to (some) of our users. Let us know if you'd like this in Asia. bit.ly/oyf1CW
□ PLoS:
EC will extend pilot OA test project from 20% to 100% of EC funded research - tinyurl.com/ECOA100
Open Biology is a fast, open access journal covering biology at the molecular and cellular level.
Open Biology will publish original, high quality research in cell biology, developmental and structural biology, molecular biology, biochemistry, neuroscience, immunology, microbiology and genetics.
・Rapid publication in a Royal Society journal
・Rigorous and constructive peer review
・Immediate open access: fully compliant with funder and institutional mandates
・E-only continuous publication model, which allows immediate citation of articles
・Author retention of copyright and liberal reuse rights via Creative Commons Attribution Licence (CC by 3.0)
・Publisher deposit of articles in PubMedCentral
・Information on individual article downloads
・High levels of author service and support
・Media promotion of articles
・free online colour
This workshop will bring together developers, curators, journal editors and researchers to discuss on the growing number of (closely related efforts) developing to catalogues of tools, databases, related data and publications.
The focus on the workshop is a strawman uniform system for describing these bio-resources, in particular, indicating in a consistent manner which community-defined standards (minimal information checklists, terminologies and exchange formats) they implement.
The Life Science Database Archive maintains and stores the datasets generated by life scientists in Japan in a long-term and stable state as national public goods. The Archive makes it easier for many people to search datasets by metadata (description of datasets) in a unified format, and to access and download the datasets with clear terms of use
01. JG Thirlwell - Susanna (Uxorial mix) 4:48
02. Achim Mohné - Milan Knizhak mix#1 (side a) 6:05
03. Jóhann Jóhannsson - Zarrin (remix) 6:01
04. Anonymous - Triple Exposure 9:10
05. Leif Elggren - No One Really Knows (destroyed) 11:46
[1 track - 37:09]
Originally Composed by Sohrab
Track 3 Mixed by Jóhann Jóhannsson at NTOV, Copenhagen, 24th May 2011
Track 4 Mastered by a different Anonymous 24th May 2011
Photography: Jon Wozencroft
The first in a series of reworkings of Sohrab material by artists showing solidarity to his cause... all label and artist money goes towards the fund for his appeal against the refusal to be granted political asylum in Germany...
This release is a fund-raiser to help pay for a lawyer to help with his appeal against the ruling. 100% of Artist and Label money from this release will be donated directly to the appeal fund.
You can donate more if you wish simply by purchasing multiple copies of this release.
The amazing visual effects in this film are complimented by the talented efforts of the sound team including Re-recording Mixers Greg Russell and Jeff Haboush, and Supervising Sound Editor and Sound Designers Ethan Van der Ryn, and Erik Aadahl.
□ phylogenomics: Jonathan Eisen
David Relman quote on a slide re human microbiome: "We are born ~ 100% human but die > 90% microbial" #microbes
The interpretation of the gene as DNA and the deciphering of the genetic code then gave rise to molecular interpretations of mutation, views that also impacted evolutionary biology, population genetics, commercial development of plants and animals, and human genetics.
This book shows how generational definitions or assessments of mutation have responded to the technologies added to science and the experiments that abounded with the inquiries of each successive generation.
Staff at an Australia library have been stunned after first edition copy of Charles Darwin's Insectivorous Plants book was returned 122 years late. http://tgr.ph/jG7Fr1
The diversity of avian plumage colors occupies only a portion (26?30%, using violet-sensitive and ultraviolet-sensitive models, respectively) of the total available avian color space, which represents all colors birds can theoretically see and discriminate.
A new study focused on a single gene, the one coding for the cannabinoid receptor 1 (CNR1) in brain cells. Participants with certain mutations in this gene spent more time looking at happy faces than others did.
With the increase of automated discovery and large-scale data collection, eurekometric research has the potential to explode. First, automated science will necessarily have the property of creating large amounts of discovery data.
Illustrative examples of automated science include the Sloan Digital Sky Survey, Lincoln Near-Earth Asteroid Program, Gordon and Betty Moore Foundation Marine Microbial Genome Sequencing Project, and the Census of Marine Life. The initial output of these projects will not be publications, but findings. Each object, such as a newly discovered asteroid, need not have its own publication, but each object can be examined separately from a eurekometric perspective.
In addition, there is the potential in such areas as automated drug discovery, automated chemical synthesis path discovery, and automated theorem proving.
An Oscar-winning producer talks about his interest in moviemaking, medicine, and scaleable (storytelling) design.
By integrating the front line medical expertise of physicians with the artistry of moviemakers, we are trying to shift the focus toward scaling health apps worldwide: We would like to develop a mobile health app that can help kids, from Los Angeles to Mumbai, make better food choices. We want to create compelling solutions to global health problems.
□ A-IMBN Research:
Driving differentiation http://nature.asia/lydQwH The elusive mechanism that promotes neuronal differentiation by blocking cell division is linked to a specific protein.
For blazing a new trail in open-access journals, inspiring broader change in scholarly publishing, and thriving along the way, SPARC (the Scholarly Publishing and Academic Resources Coalition) has named the Public Library of Science’s (PLoS) PLoS ONE as the SPARC Innovator for June 2011.
Researchers from the Center for Biomedical Informatics (CBMi) at The Children’s Hospital of Philadelphia have created a free iPad app called Genome Wowser, which provides a mobile interface to data from the UC Santa Cruz genome browser, one of the three major portals to the reference genome sequence established in 2000.
Three major life science funders, the Howard Hughes Medical Institute, the Wellcome Trust, and the Max Planck Society today announced that they intend to fund the launch of what they hope will become a top-tier biomedical and life science journal to rival the likes of Nature and the New England Journal of Medicine -- and it might seem the Public Library of Sciences' (PLoS] flagship open access biomedical journals.
The journal, which they expect to begin publishing summer 2012, has yet to be given a name, but it would be online-only and open-access, with -- initially at least ? no charges for authors to publish papers, by contrast to most open access journals such as PLoS Biology which charge authors an article fee.
□ bffo: BF Francis Ouellette
New in NAR: The Annual Nucleic Acids Research Web Server Issue link to Gary Benson's editorial: http://bit.ly/lKPpRq#bioinformatics
The 2011 Web Server Issue of Nucleic Acids Research is the ninth in a series of annual special issues dedicated to web-based software resources for analysis and visualization of molecular biology data. It is freely available online under NAR's open access policy. The present issue reports on 92 web servers.
□ 454Sequencing:
Roche Launches GS FLX+ System Offering High-Quality, Sanger-like Reads with the Power of Next-Generation Throughput bit.ly/kcOvuC
Anti-DNA:RNA Antibodies and Silicon Photonic Microring Resonators: Increased Sensitivity for Multiplexed microRNA Detection
In this paper, we present a method for the sensitive detection of microRNAs (miRNAs) utilizing an antibody that specifically recognizes DNA:RNA heteroduplexes and a silicon photonic microring resonator array transduction platform. Microring resonator arrays are covalently functionalized with DNA capture probes that are complementary to solution phase miRNA targets.
Following hybridization on the sensor, the anti-DNA:RNA antibody is introduced and binds selectively to the heteroduplexes, giving a larger signal than the original miRNA hybridization due to the increased mass of the antibody, as compared to the 22-mer oligoribonucleotide.
NBDC / DBCLS BioHackathon 2011 will be held in Kyoto, Japan. Main focus of the BioHackathon is to develop technologies for handling Linked Data in life science. We will discuss, explore and develop SPARQL endpoints, semantic web services, triple stores, ontologies, natural language processing, visualization and Open Bio* tools to utilize RDF data.
Disc 2
01. Aeron Aether & Embliss - A New Dawn (Reconstruction)
02. Janeiro & Sovt - Dreams Of The Sea
03. Mike St Jules - Vespera (Reconstruction)
04. Jahawi - Nairobi to London
05. Solarstone - Touchstone (Orkidea Remix)
06. Medway - Resurrection (Proff Remix)
07. Baltic Sound - Searchers Lane
08. Ozo Effy - White Wind
09. Peter Liu - City Of Dreams
10. Majera - Escapade
11. Tilt - I Dream (Nick Rowland Remix)
12. Almar - Wasted Time
13. Active Limbic System - Vanity
14. DJ Orion & J.Shore Architect's Dream (Dub)
Compiled & mixed by Solarstone (Richard Mowatt)
Design by Andrew Debens
Website by George Bitiusca
Original Artwork by Richard Sinmpkins
Disc 1
1. Le Nocturne De Lumiere (Cedric Gervais Remix)
2. Rose of Jericho (Adam K & Soha Remix)
3. Always (Funkagenda Mix)
4. Love Can Kill You (Moonbeam Remix)*
5. The Emergency (Marcus Schössow Remix)
6. Every Other Way (Josh Gabriel Remix)
7. Suddenly (Ferry Corsten Remix)
8. Forget Me (Mr Sam Remix)
9. The Unbreakable (Grayarea Mix)*
Disc 2
1. The Emergency (Lost Stories Remix vs. Dragon, Jontron, Manufactured Superstars Remix)*
2. Rose of Jericho (Sultan & Ned Shepard Remix)
3. A Million Stars (Digital Stories Remix)*
4. The Light In Things (tyDi Remix)*
5. Always (Chicane Remix)
6. The Unbreakable (Breakfast Remix)
7. Forget Me (Michael Cassette Mix)
8. Every Other Way (Armin van Buuren Remix)
Mixed by BT
Creative Direction : BT & Gavin Taylor
Art Direction / Design / Illustration : Gavin Taylor
05. Ballad Of The Sad Young Men Frances Landesman / Thomas Wolf
06. Oz Guizos Hermeto Pascoal
07. Song For Swirek
in loving memory of Marek SwierkowskiMarcin Wasilewski
08. Woke Up In The Desert Marcin Wasilewski
09. Big Foot Paul Bley
10. Lugano Lake Marcin Wasilewski
Marcin Wasilewski piano Slawomir Kurkiewicz double-bass Michal Miskiewicz drums
Recorded August 2010
Auditorio Radiotelevisione svizzera, Lugano
Engineer: Stefano Amerio
Technical Assistant: Marco Strigl (RSI)
Cover Photo: Thomas Wunsch
Liner Photo: Thomasz Sikora
Design: Sascha Kleis
Produced by Manfred Eicher
“Marcin Wasilewski does not think like other jazz pianists, His improvisational underpinning, his sense of musical space and his aural imagery are so fresh they are initially mysterious," - Thomas Conrad, JazzTimes
ハンス・アイスラー作曲の"An den kleinen Radioapparat”は、後にStingによってアレンジされた“The Secret Marriage”として有名になった歴史的佳曲。しかしMarcinは、当時ブレヒトとアイスラーが込めた政治・社会的思想を色濃く残した形で再解釈を施しているのだそう。
最初のオリジナル曲である"Night Train To You"では、特徴的なコードとループの組み合わせで『静と動』を表現した作品。楽曲は駅に近づくにつれてテンポを緩め、最期のセクションでは初期の主題に基づいたインプロヴィゼーションが展開される。
表題曲"Faithful"は、Marcin Wasilewski Trio結成のルーツとなり、三人のジャズに対する共通のインスピレーションとなOrnette Colemanの1966年のアルバム、 “The Empty Foxhole”から。
