Removal of prions from blood, plasma and other liquids
Patent number: 6221614
Filing date: Jan 20, 1999
Issue date: Apr 24, 2001
Inventors: Stanley B. Prusiner, Jiri G. Safar
Devices such as flow through columns, substrates such as spherical polymer beads, and methods of using such to remove prions from any liquid sample are disclosed. A surface of a substrate is coated with a prion complexing agent, such as a salt of phosphotungstic acid. Blood or plasma passing through a column containing beads coated with prion complexing agent are rendered prion free.
Patent number: 6221614
Filing date: Jan 20, 1999
Issue date: Apr 24, 2001
Inventors: Stanley B. Prusiner, Jiri G. Safar
Devices such as flow through columns, substrates such as spherical polymer beads, and methods of using such to remove prions from any liquid sample are disclosed. A surface of a substrate is coated with a prion complexing agent, such as a salt of phosphotungstic acid. Blood or plasma passing through a column containing beads coated with prion complexing agent are rendered prion free.