BMJ Case Reports 2013; doi:10.1136/bcr-2013-200983
Evidence for cytomegalovirus-induced haemophagocytic syndrome in a young patient with AIDS
Kosuke Ohkuma1, Takeshi Saraya1, Mitsuru Sada1, Shin Kawai2
1Department of Respiratory Medicine, Kyorin University School of Medicine, Mitaka, Japan
2Department of Infectious Disease, Kyorin University School of Medicine, Mitaka, Japan
Correspondence to
Dr Takeshi Saraya
Summary
A 29-year-old man with HIV infection was referred to our department because of a 1-month history of low-grade fever and fatigue. Bone marrow aspiration and biopsy showed findings consistent with haemophagocytic syndrome (HPS), and immunohistochemical assessment showed cytomegalovirus (CMV) infection. HIV-associated HPS can occur at any stages of HIV disease and requires diverse differential diagnosis. CMV-associated HPS (CMV-HPS) in patients with HIV infection is relatively rare, but the present case showed that the clinicians should consider the possibility of CMV-HPS as a clinical feature of CMV infection.
Evidence for cytomegalovirus-induced haemophagocytic syndrome in a young patient with AIDS
Kosuke Ohkuma1, Takeshi Saraya1, Mitsuru Sada1, Shin Kawai2
1Department of Respiratory Medicine, Kyorin University School of Medicine, Mitaka, Japan
2Department of Infectious Disease, Kyorin University School of Medicine, Mitaka, Japan
Correspondence to
Dr Takeshi Saraya
Summary
A 29-year-old man with HIV infection was referred to our department because of a 1-month history of low-grade fever and fatigue. Bone marrow aspiration and biopsy showed findings consistent with haemophagocytic syndrome (HPS), and immunohistochemical assessment showed cytomegalovirus (CMV) infection. HIV-associated HPS can occur at any stages of HIV disease and requires diverse differential diagnosis. CMV-associated HPS (CMV-HPS) in patients with HIV infection is relatively rare, but the present case showed that the clinicians should consider the possibility of CMV-HPS as a clinical feature of CMV infection.
