【論】Efron,2001,Empirical Bayes analysis of a ～

Bradley Efron, Robert Tibshirani, John D.Storey, and Virginia Tusher.
Empirical Bayes Analysis of a Microarray Experiment.
Journal of the American Statistical Association, 96: 1151-1160.
[PDF][Web Site]

・ベイズ統計を使ってデータの次元を下げる手法について。
・データ：ヒト、Lymphoblastoid cell lines GM14660 and GM08925、Affy.、6810遺伝子、8サンプル

・「The empirical Bayes inferences are closely related to the frequentist false discovery rate (FDR) criterion.」
・目的「One goal in this article is to provide a method for comparing the statistical efficiency of different data reduction strategies.」

・ベイズ統計とFDRの何たるかがわかっていないので、サッパリ内容つかめず。

《チェック論文》
・Kerr MK, Churchill GA.,Bootstrapping cluster analysis: assessing the reliability of conclusions from microarray experiments., Proc Natl Acad Sci USA. 2001 Jul 31;98(16):8961-5. Epub 2001 Jul 24.