Raymond J. Cho, Micheline Fromont-Racine, Lisa Wodicka, Becket Feierbach, Timothy Stearns, Pierre Legrain, David J. Lockhart, and Ronald W. Davis
Parallel analysis of genetic selections using whole genome oligonucleotide arrays.
Proc. Natl Acad. Sci. USA 95, 3752-3757 (1998).
[PDF][Web Site]
・DNAマイクロアレイ分野の初期における、Affymetrixのチップを使った基礎的な研究。チップを作成し、遺伝子発現量をうまく測定できるかを検証する。
・目的「We present an alternative approach in which identification of nucleic acids is accomplished by direct hybridization to high-density oligonucleotide arrays.」
・利点「The use of array hybridization to analyze results from these screens would eliminate the need to maintain large numbers of individual clones in tissue culture until they can be sequenced.」
Parallel analysis of genetic selections using whole genome oligonucleotide arrays.
Proc. Natl Acad. Sci. USA 95, 3752-3757 (1998).
[PDF][Web Site]
・DNAマイクロアレイ分野の初期における、Affymetrixのチップを使った基礎的な研究。チップを作成し、遺伝子発現量をうまく測定できるかを検証する。
・目的「We present an alternative approach in which identification of nucleic acids is accomplished by direct hybridization to high-density oligonucleotide arrays.」
・利点「The use of array hybridization to analyze results from these screens would eliminate the need to maintain large numbers of individual clones in tissue culture until they can be sequenced.」
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