サウジの健康成人にはMERS抗体陽性者がいっぱい？（マーズコロナウイルス ＭＥＲＳ-ＣｏＶ マーズ）

ラクダに接触していないのに、（さらに医療従事者でもないのに）、MERS-CoVに感染してしまったという例が後を絶ちません。このナゾの感染例のヒントになるかもしれない報告。

• サウジアラビアにて１５歳以上の健康成人対象に血清検査。地理的には全１３州地方カバー。さらに、羊飼いと食肉処理業者も追加。ｎ＝10009
• MERS-CoV抗体は15例から検出。１３地方中６地方で検出。陽性検出者の平均年齢は、これまで感染報告例の平均より低かった。
• 女性より男性の方が抗体陽性率高かった。
• 海外地方より内陸部で抗体陽性率高かった（0.26％vs0.02％）。
• 羊飼いでは平均の15倍抗体陽性率高く（2.3％）、食肉処理業者では２３倍高かった（3.6％）。

サウジ国土の半分にわたって、健常成人のMERSの抗体陽性者がいっぱいいて、だから一見元気な人から感染してる可能性があちこちである。。。という仮説になりそうです。差別の芽にもなりそうな危うさはありますから注意しなければなりませんが、謎がひとつ解決しそうな感じです。

ソースはLancet
http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(15)70090-3/abstract?hc_location=ufi

Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study

Marcel A Müller

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Marcel A Müller

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• Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

, PhD

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Benjamin Meyer

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Benjamin Meyer

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• Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

, MSc

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Victor M Corman

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Victor M Corman

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• Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

• German Centre for Infection Research, Partner Site Bonn-Cologne, Bonn, Germany

, MD

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Malak Al-Masri

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Malak Al-Masri

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• King Abdulaziz Medical City & Advisor Royal Court, Riyadh, Saudi Arabia

, BSc

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Abdulhafeez Turkestani

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Abdulhafeez Turkestani

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• King Abdulaziz Medical City & Advisor Royal Court, Riyadh, Saudi Arabia

• Makkah Regional Health Affairs, Ministry of Health, Makkah, Saudi Arabia

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Daniel Ritz

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Daniel Ritz

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• Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

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Andrea Sieberg

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Andrea Sieberg

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• Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

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Souhaib Aldabbagh

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Souhaib Aldabbagh

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• Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

, DVM

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Berend-J Bosch

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Berend-J Bosch

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• Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands

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Erik Lattwein

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Erik Lattwein

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• Euroimmun AG, Lübeck, Germany

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Raafat F Alhakeem

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Raafat F Alhakeem

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• King Abdulaziz Medical City & Advisor Royal Court, Riyadh, Saudi Arabia

, MD

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Abdullah M Assiri

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Abdullah M Assiri

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• King Abdulaziz Medical City & Advisor Royal Court, Riyadh, Saudi Arabia

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Ali M Albarrak

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Ali M Albarrak

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• Saudi Center for Disease Control, Riyadh, Saudi Arabia

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Ali M Al-Shangiti

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Ali M Al-Shangiti

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• National Health Laboratory, Riyadh, Saudi Arabia

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Jaffar A Al-Tawfiq

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Jaffar A Al-Tawfiq

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• Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia

• Indiana University School of Medicine, Indianapolis, IN, USA

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Paul Wikramaratna

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Paul Wikramaratna

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• Institute of Evolutionary Biology, University of Edinburgh, Centre for Infection, Immunity and Evolution, Edinburgh, UK

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Abdullah A Alrabeeah

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Abdullah A Alrabeeah

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• King Abdulaziz Medical City & Advisor Royal Court, Riyadh, Saudi Arabia

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Prof Christian Drosten

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Christian Drosten

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• Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

• German Centre for Infection Research, Partner Site Bonn-Cologne, Bonn, Germany

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• Prof Christian Drosten, Institute of Virology, University of Bonn Medical Centre, Bonn, D-53127, Germany

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Christian Drosten

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• Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

• German Centre for Infection Research, Partner Site Bonn-Cologne, Bonn, Germany

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• Prof Christian Drosten, Institute of Virology, University of Bonn Medical Centre, Bonn, D-53127, Germany

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Prof Ziad A Memish

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Ziad A Memish

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• King Abdulaziz Medical City & Advisor Royal Court, Riyadh, Saudi Arabia

• Alfaisal University, Riyadh, Saudi Arabia

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• Correspondence to: Prof Ziad A Memish, Ministry of Health, Preventive Medicine, PO Box 54146, Riyadh 11514, Saudi Arabia

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Ziad A Memish

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• King Abdulaziz Medical City & Advisor Royal Court, Riyadh, Saudi Arabia

• Alfaisal University, Riyadh, Saudi Arabia

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• Correspondence to: Prof Ziad A Memish, Ministry of Health, Preventive Medicine, PO Box 54146, Riyadh 11514, Saudi Arabia

^†

^†Contributed equally

Published Online: 08 April 2015