# 地球の冷凍庫が壊れようとしています
# なんで30年以上も放置されていたのか…
# 牛のボツリヌス菌はヒトにも感染するんだろうか?
# 今やらないと、数年後には費用が何倍にもなってしまう…ちゅうか、駆除も出来なくなるかも…
# 限られた数の個体だけで維持していくのはただでさえ難しいのに…
Andrew J French, Catharine A Adams, Linda S Anderson, John R Kitchen, Marcus R Hughes, Samuel H Wood.
Stem Cells, Express | doi:10.1634/stemcells.2007-0252
Nuclear transfer stem cells (NTSC) holds considerable promise in the field of regenerative medicine and cellbased drug discovery. In this study, a total of 29 oocytes were obtained from three young (20–24 y) reproductive egg donors who had been successful in previous cycles. These oocytes, deemed by intended parents to be in excess of their reproductive needs, were donated for research without financial compensation by both the egg donor and intended parents after receiving informed consent. All intended parents successfully achieved ongoing pregnancies with the oocytes retained for reproductive purposes. Mature oocytes, obtained within 2 h following transvaginal aspiration, were enucleated using one of two methods, extrusion or aspiration, after 45 min incubation in Cytochalasin B. Rates of oocyte lysis or degeneration did not differ between the two methods. Somatic cell nuclear transfer (SCNT) embryos were constructed using two established adult male fibroblast lines of normal karyotype. High rates of pronuclear formation (66%), early cleavage (47%) and blastocyst (23%) development were observed following incubation in standard IVF culture media. One cloned blastocyst was confirmed by DNA and mtDNA fingerprinting analyses and DNA fingerprinting of two other cloned blastocysts indicated they were also generated by SCNT. Blastocysts were also obtained from a limited number of parthenogenetically activated oocytes. This study demonstrates, for the first time, that SCNT can produce human blastocyst stage embryos using nuclei from a differentiated adult somatic cell, and provides new information on methods that may be needed for a higher level of efficiency for human therapeutic cloning.
# 論文などが分かったので内容再掲
# JJAPのことかと思ったが見つけられず…
# 影響が現れる前に調べるというのは、これまた難しいことです
# 特定の症例に特化したセンターを作るとはまた珍しい…
# 腸内フローラは未開の最後の臓器です
# お、「オランダの糖尿病専門誌」?…何故に?
# へぇ!シワの構造が丸分かり
Masako Kakizaki, Shinichi Kuriyama, Yuki Sato, Taichi Shimazu, Kaori Matsuda-Ohmori, Naoki Nakaya, Akira Fukao, Shin Fukudo, Ichiro Tsuji.
Journal of Psychosomatic Research 64, 71-80 (2008) | doi:10.1016/j.jpsychores.2007.07.008
Objective# なんでわざわざ「国際心身医学会誌」なんて日本語に直そうとするかねぇ
Obesity is an increasingly prevalent public health problem worldwide, and is associated with a higher risk of developing various noncommunicable diseases. To further examine the association between personality and overweight, obesity, or underweight, we conducted a cross-sectional analysis in Japan. We hypothesized that extraversion and psychoticism would have a positive association with overweight, and that neuroticism and lie would have an inverse association with overweight, whereas the association between personality and underweight would be the reverse image of overweight.
Methods
In 1990, 30,722 subjects (40–64 years of age) completed a self-administered questionnaire including body weight and height and the Japanese version of the Eysenck Personality Questionnaire-Revised Short Form. Multivariate logistic regression analysis was used to calculate odds ratios for overweight [body mass index (BMI)≥25.0 kg/m2] or underweight (BMI<18.5) relative to each category on the personality subscale.
Results
In men and women, extraversion and psychoticism had positive associations with overweight, whereas neuroticism had an inverse association. Lie had an inverse association with overweight in men. In men and women, only extraversion had an inverse association with underweight and neuroticism had a positive association with underweight.
Conclusion
Our findings indicate that personality is associated with both overweight and underweight. These results may provide clues to devising more effective measures for preventing overweight, obesity, or underweight or for weight control intervention.
# 表示云々の前に、経済的に十分ペイするんだろうか?
# 論文掲載はまだの模様…「米地球物理学連合」=「American Geophysical Union」ね
# これはいい方法ですね
# 今度やってみようっと
# オープンな大量のデータを格納するにはもってこいかも
# 凄いな、この写真
http://web.kyoto-inet.or.jp/people/sugicom/kazuo/neta/bake38.html
> 一緒にこんなものを添えてみるのは如何でしょうか?
まず間違いなく食欲が失せるので、ダイエットにピッタリでしょう