加熱によるSARS-CoV2への影響

Influence of Different Inactivation Methods on Severe Acute Respiratory Syndrome Coronavirus 2 RNA Copy Number

JCM 2020 

56℃30分では約5割のウイルス量減少に対して100℃、12０℃では20分でほぼ0になる。（先行研究でも同様の見解。高温加熱による不活化はRNAに対するダメージが大きい）

TRIzol treatment destroyed 47.54% of N gene and 39.85% of ORF 1ab. For samples treated at 56°C for 30 min, the copy number of N gene and ORF 1ab was reduced by 48.55% and 56.40%, respectively. Viral RNA copy number dropped by 50–66% after 80°C heating for 20 min. Nearly no viral RNA was detected after autoclaving at 121°C or boiling at 100°C for 20 min.