New white paper sheds light on flow chemistry

A drive to improve quality, yield, and cycle time coupled withdesire for high personal performance has led to novel chemistrymethodologies enabling a wide range of reactions in productdevelopment. A METTLER TOLEDO white paper explores theinterrelationship of two of these critical methodologies, flowchemistry and mid-infrared spectroscopy , in today"s highly competitive R&D environment. METTLER TOLEDO is pleased to announce that a new white paperentitled "Enhanced Development and Control of ContinuousProcesses: A Review of Modern Technologies" is joining thecompany"s extensive collection of thought-leadershipresources. The new paper reviews flow chemistry"s revolutionary role inpharmaceutical and fine chemistry environments, including itsability to enhance product quality, increase yield, elucidatesynthetic route and improve reaction safety, all while reducingcycle time, which is critical to reducing development costs andcapturing market share in today"s competitive manufacturingarena.

The paper explores mid-infrared (IR) spectroscopy as a convenient and nondestructive method for real-time inlineflow chemistry monitoring, because it allows real-timedata-gathering on the formation of products and reactiveintermediates. This instantaneous feedback on how changing aparameter such as flow rate or reaction temperature affects areaction enables faster, safer and more cost-effective processoptimization. The intensity of IR energy absorbed at a particular wavelength isdefined by Beer"s law to be proportional to concentration,making it possible to track the relative concentration ofindividual reaction components using mid-IR-enabled technology.Employing this type of technology not only results in improvedreaction understanding; it also allows researchers to overcome whatused to be significant optimization issues, such as making acontrolled addition of reagent stoichiometries to a product streamusing output data from a prior reaction stage when performingmulti-step synthesis. The paper describes specific instances where mid-IR technology andflow chemistry principles were applied to monitor productstreams/dispersion effects in continuous flow reactors and allowedsuccessful third-stream reagent addition, helping to eliminate poorreaction control and the waste it produces. For a copy of the white paper, please visit: /flowchemwp About METTLER TOLEDO METTLER TOLEDO provides the enabling technology, software andpeople that can help build a seamless workflow to translate benchscale chemistry into a commercial process.

For more than 20 years,our enabling tools and services have been a strategic resourceproviding critical information for thousands of developmentscientists and engineers. Companies have used that knowledge toaccelerate the discovery, development and scale-up of new chemicalprocesses spanning the chemical and biopharmaceutical industries.For more, visit .
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Hero driver gives spiritual support to rise of china - Door Release Push Button Manufacturer

The Hero driver Wu Bin, like the most beautiful female teacher andmost beautiful mother, is a bright landmark of the current China.The rise of a great power does not mean only the economic miracleand material civilization. Without a strong enough spiritualsupport, a great power will not last and will not be recognized andaccepted by the world. Wu Bin is an ordinary Chinese person but is also a hero. The heroicdeed of an ordinary person is making the world approach Chinesepeople once again and helping the touched and shocked worldunderstand the spiritual support to the rise of China. Smart Cards Access Control

The U.S. Associated Press published an article, "China HailsBus Driver Who Saved Passenger" on June 3 to report on Wu Binand his act at the last moment of his life. The report said that inthis increasingly competitive and even cold world, Wu'sselflessness and courage have carried forward the culturaltradition of China and will encourage people to shoulder socialresponsibilities bravely. Many media groups, including theWashington Post and the website of the American BroadcastingCompany, have republished this report. Door Release Push Button Manufacturer

On social networking sites,including facebook, twitter and YouTube, many praised him as"a great hero of ordinary people" and "a truehero." The sympathy of souls is more powerful than the cold exchange ofinterests and is a footstone for the platform of trust and afoundation of the harmonious development, whether in theinterpersonal relations or international relations. The rise of a great power does not mean only the economic miracleand material civilization. Without a strong enough spiritualsupport, a great power will not last and will not be recognized andaccepted by the world. The current China is a diversified China. Magnetic Door Contact Switch

While the economy isdeveloping rapidly and the social transformation is accelerating,some moral and spiritual problems have also appeared in the Chinesesociety. The severe environmental problems and food safety problemsnot only need all walks of life to reflect but also havestrengthened the outside world's doubt on the rise of China. How should the value orientation of Chinese people be understood?How should the mainstream spiritual world of Chinese people beregarded? The ordinary and kind Chinese people, including theheroic driver, most beautiful female teacher, most beautifulmother, have shown the simplest, greatest and most precious partsof the human being to the world and will help people find answersof these questions. The Hero driver Wu Bin, like the most beautiful female teacher,most beautiful mother, is a bright landmark of the current China.If a country can touch people by its spiritual elements, it willdefinitely have a lot of friends and be respected and admired byothers. Read the Chinese version: , source: People's Daily, author: Zhong Sheng.