| 論文番号 | 著者名 | 論文タイトル名 | 発表雑誌名 | 巻、号 | ページ | 出版年 |
| 論文#10 | Kase H, Hattori Y, Jojima T, Okayasu T, Tomizawa A, Suzuki K, Banba N, Monden T, Satoh H, Akimoto K, Kasai K. | Globular adiponectin induces adhesion molecule expression through the sphingosine kinase pathway in vascular endothelial cells. | Life Sciences | 81(11) | 939-943 | 2007 |
| 論文番号 |
指摘項目番号 | 不正が疑われる図の番号 |
| 論文#10 | 指摘項目No.27 |
Figure 3 (C) |
(A)- 指摘項目No.27
論文#10のFigure 3 (C)の再下段のMCP-１の画像全６列分は、
論文#13のFigure 4 (A)のiNOSの画像全６列分（Fruct, Fruct/BH4の画像）や、
論文#16のFigure 5 (b)のiNOS Proteinの画像右６列分（BH4 only, AngII, AngII/BH4の画像）と、
類似しており、画像の流用（データ捏造）が疑われます。
論文#10のFigure 3 (C)の再下段のMCP-１の画像全６列分は、
論文#13のFigure 4 (A)のiNOSの画像全６列分（Fruct, Fruct/BH4の画像）や、
論文#16のFigure 5 (b)のiNOS Proteinの画像右６列分（BH4 only, AngII, AngII/BH4の画像）と、
類似しており、画像の流用（データ捏造）が疑われます。
研究不正に関連する図（Figure）
↓論文#10のFigure 3 (C)
Copyright (C) Elsevier Inc. All rights reserved.
Life Sciences 81 (2007) 939–943
Fig. 3. SKase activation is involved in globular adiponectin-induced activation
of NF-κB and adhesion molecule expression. (A) Treatment of cells with SKase
siRNA inhibited globular adiponectin-induced NF-κB activation. Data are
means±SD of at least three independent repetitions. ⁎Pb0.01 compared with
the value of gAd. (B) Treatment of cells with SKase siRNA markedly decreased
adiponectin-induced mRNA levels of adhesion protein expression. White bars:
control, grey bars: control treated with SKase siRNA, black bars: gAd, hatched
bars: gAd treated with SKase siRNA. Data are means±SD of at least three
independent repetitions and are shown as ratios against GAPDH. ⁎Pb0.01
compared with the value of gAd. (C) Treatment of cells with siRNA suppressed
globular adiponectin-induced protein levels of VCAM-1, ICAM-1, E-selectin,
and MCP-1. Experiments were performed in duplicate.
