スウェーデン・イエテボリ大学のウエブサイトに面白い報告があった。
骨吸収を伴うインプラントの出血、排膿、歯茎の後退（歯周ポケット６mm以上）のインプラント周囲炎を起こすのは、喫煙者で６９％にも達する。その好発部位は、下顎前歯部で最も多く、５２％も認められる。
術後感染したインプラント一年後の平均的骨吸収量は1.65mmであり、2mm以上の発生率は３２％にも及びます。
年々骨吸収して、いずれは感染したインプラントが駄目になることを考えると、やはり喫煙者のインプラントにはリスクが伴うことが良く分かる。
このデータは６２２名、３４１３本のインプラントを対象とした解析の結果、骨吸収発生率12.4％であった。
非常に興味深いデータであるが、解析対象がブローネンマルクインプラントであり、定期的にメンテナンスをしている患者さんである。
なお、プラットホームスイッチングできる最新のインプラントではないのでなんとも言えないが、考え深いデータである。
以下原文です。
Prevalence, extent and severity of peri-implantitis
Akademisk avhandling
som för avläggande av odontologie doktorsexamen vid Göteborgs Universitet
kommer att offentligen försvaras i föreläsningssal 3, Institutionen för Odontologi
Medicinaregatan 12E, Göteborg, fredagen den 18 december 2009, kl. 09.00
av
Christer Fransson
Leg. tandläkare
Fakultetsopponent:
Professor Stefan Renvert, sektionen för hälsa och samhälle
Högskolan i Kristiansstad
Kristiansstad
Avhandlingen baseras på följande delarbeten:
I. Fransson, C., Lekholm, U., Jemt, T., Berglundh, T. (2005) Prevalence of
subjects with progressive bone loss at implants. Clinical Oral Implants Research 16:
440-446.
II. Fransson, C., Wennström, J., Berglundh, T. (2008) Clinical characteristics at
implants with a history of progressive bone loss. Clinical Oral Implants Research
19: 142-147.
III. Fransson, C., Wennström, J., Tomasi, C., Berglundh, T. (2009) Extent of periimplantitis-
associated bone loss. Journal of Clinical Periodontology 36: 357-363.
IV. Fransson, C., Tomasi, C., Sundén Pikner, S., Gröndahl, K., Wennström, J.,
Leyland, A.H., Berglundh, T. Severity and pattern of peri-implantitis-associated
bone loss. Submitted to Journal of Clinical Periodontology.
Abstract
Prevalence, extent and severity of peri-implantitis
Christer Fransson
Department of Periodontology, Institute of Odontology, the Sahlgrenska Academy at
University of Gothenburg, Box 450, 405 30 Göteborg, Sweden.
Peri-implantitis is a disorder that affects the tissues surrounding a functional implant.
Peri-implantitis can lead to implant loss and impaired function. There is limited
information regarding the prevalence of peri-implantitis. In addition the extent of the
disease and pattern of bone loss are poorly described.
The objective of the present series of studies was to assess the prevalence of subjects
exhibiting progressive bone loss at implants supporting fixed prosthesis (Study I) and
to examine the clinical characteristics at implants with radiographic evidence of
progressive bone loss (Study II). Furthermore, the extent, severity and pattern of periimplantitis-
associated bone loss were evaluated (Study III and Study IV).
Bone-level assessments were performed in intra-oral radiographs and the clinical
conditions of the peri-implant tissues were examined. A multilevel growth curve model
was used to analyze the pattern of bone loss.
It was demonstrated that 28% of subjects had one or more implants with progressive
bone loss. The individuals in this group carried a significantly larger number of
implants than the subjects in whom no implants with progressive loss were detected
(6.0 vs. 4.8). Out of the total 3413 implants included in the study 12.4 percent
demonstrated progressive bone loss (Study I).
Clinical signs of pathology were more frequent at implants with than without
progressive bone loss. Smokers had larger numbers of affected implants than nonsmokers
and the proportion of affected implants that exhibited pus and PPD 6 mm
was higher in smokers than in non-smokers. The findings of pus, recession and PPD
6mm at an implant in a smoking subject had a 69% accuracy in identifying history
of progressive bone loss (Study II).
About 40% of the implants in each affected subject had peri-implantitis. The
proportion of such implants varied between 30 and 52% in different jaw positions.
The most common position was the lower front region. (Study III).
The average bone loss after the first year of function at the affected implants was 1.65
mm and 32% of the implants demonstrated bone loss 2 mm. The bone loss showed
a non-linear pattern and the rate of bone loss increased over time (Study IV).
Key words: bone loss, complications, dental implants, implant position, human, multilevel analyses,
peri-implantitis, radiographs, smoking.
ISBN 978-91-628-7953-2
骨吸収を伴うインプラントの出血、排膿、歯茎の後退（歯周ポケット６mm以上）のインプラント周囲炎を起こすのは、喫煙者で６９％にも達する。その好発部位は、下顎前歯部で最も多く、５２％も認められる。
術後感染したインプラント一年後の平均的骨吸収量は1.65mmであり、2mm以上の発生率は３２％にも及びます。
年々骨吸収して、いずれは感染したインプラントが駄目になることを考えると、やはり喫煙者のインプラントにはリスクが伴うことが良く分かる。
このデータは６２２名、３４１３本のインプラントを対象とした解析の結果、骨吸収発生率12.4％であった。
非常に興味深いデータであるが、解析対象がブローネンマルクインプラントであり、定期的にメンテナンスをしている患者さんである。
なお、プラットホームスイッチングできる最新のインプラントではないのでなんとも言えないが、考え深いデータである。
以下原文です。
Prevalence, extent and severity of peri-implantitis
Akademisk avhandling
som för avläggande av odontologie doktorsexamen vid Göteborgs Universitet
kommer att offentligen försvaras i föreläsningssal 3, Institutionen för Odontologi
Medicinaregatan 12E, Göteborg, fredagen den 18 december 2009, kl. 09.00
av
Christer Fransson
Leg. tandläkare
Fakultetsopponent:
Professor Stefan Renvert, sektionen för hälsa och samhälle
Högskolan i Kristiansstad
Kristiansstad
Avhandlingen baseras på följande delarbeten:
I. Fransson, C., Lekholm, U., Jemt, T., Berglundh, T. (2005) Prevalence of
subjects with progressive bone loss at implants. Clinical Oral Implants Research 16:
440-446.
II. Fransson, C., Wennström, J., Berglundh, T. (2008) Clinical characteristics at
implants with a history of progressive bone loss. Clinical Oral Implants Research
19: 142-147.
III. Fransson, C., Wennström, J., Tomasi, C., Berglundh, T. (2009) Extent of periimplantitis-
associated bone loss. Journal of Clinical Periodontology 36: 357-363.
IV. Fransson, C., Tomasi, C., Sundén Pikner, S., Gröndahl, K., Wennström, J.,
Leyland, A.H., Berglundh, T. Severity and pattern of peri-implantitis-associated
bone loss. Submitted to Journal of Clinical Periodontology.
Abstract
Prevalence, extent and severity of peri-implantitis
Christer Fransson
Department of Periodontology, Institute of Odontology, the Sahlgrenska Academy at
University of Gothenburg, Box 450, 405 30 Göteborg, Sweden.
Peri-implantitis is a disorder that affects the tissues surrounding a functional implant.
Peri-implantitis can lead to implant loss and impaired function. There is limited
information regarding the prevalence of peri-implantitis. In addition the extent of the
disease and pattern of bone loss are poorly described.
The objective of the present series of studies was to assess the prevalence of subjects
exhibiting progressive bone loss at implants supporting fixed prosthesis (Study I) and
to examine the clinical characteristics at implants with radiographic evidence of
progressive bone loss (Study II). Furthermore, the extent, severity and pattern of periimplantitis-
associated bone loss were evaluated (Study III and Study IV).
Bone-level assessments were performed in intra-oral radiographs and the clinical
conditions of the peri-implant tissues were examined. A multilevel growth curve model
was used to analyze the pattern of bone loss.
It was demonstrated that 28% of subjects had one or more implants with progressive
bone loss. The individuals in this group carried a significantly larger number of
implants than the subjects in whom no implants with progressive loss were detected
(6.0 vs. 4.8). Out of the total 3413 implants included in the study 12.4 percent
demonstrated progressive bone loss (Study I).
Clinical signs of pathology were more frequent at implants with than without
progressive bone loss. Smokers had larger numbers of affected implants than nonsmokers
and the proportion of affected implants that exhibited pus and PPD 6 mm
was higher in smokers than in non-smokers. The findings of pus, recession and PPD
6mm at an implant in a smoking subject had a 69% accuracy in identifying history
of progressive bone loss (Study II).
About 40% of the implants in each affected subject had peri-implantitis. The
proportion of such implants varied between 30 and 52% in different jaw positions.
The most common position was the lower front region. (Study III).
The average bone loss after the first year of function at the affected implants was 1.65
mm and 32% of the implants demonstrated bone loss 2 mm. The bone loss showed
a non-linear pattern and the rate of bone loss increased over time (Study IV).
Key words: bone loss, complications, dental implants, implant position, human, multilevel analyses,
peri-implantitis, radiographs, smoking.
ISBN 978-91-628-7953-2