Welcome to Zou Lab Welcome to our lab at College of Chemistry and Molecular Engineering, Peking University!
We aim to invent chemical and biophysical tools to probe neuronal structure and activity at high spatial and temporal resolutions. We apply these tools to investigate the underlying physical forces, chemical signaling, and biological macromolecules that give rise to neuronal functions. Examples are fluorescent sensors, engineered enzymes, custom-built microscopes and software, etc.
Our methods are drawing from a wide range of techniques, including Biophysics, Protein engineering, Molecular Biology, Chemical Synthesis, Fluorescence Microscopy and Quantitative Modeling.
Current research projects include:
Optical mapping of action potential waveforms with genetically-encoded voltage indicators Chemical labeling technique for mapping the localization of biomolecules in living cells Proximity tagging methods for profiling synaptic protein synthesis Selected PublicationsMore
Bright and fast multicoloured voltage reporters via electrochromic FRET P. Zou†, Y. Zhao† et al. Nat. Commun. (2014)
Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging H. W. Rhee†, P. Zou† et al. Science (2013)
Voltage imaging with genetically encoded indicators Y. Xu, P. Zou#, and A. E. Cohen# Curr. Opin. Chem. Biol. (2017) Genetically-encoded voltage indicators L. Peng†, Y. Xu†, and P. Zou Chin. Chem. Lett. (2017) Recent NewsMore Hybrid is better! 01 Jan,2018 Our work on hybrid voltage indicator is officially accepted in Angewandte Chemie International Edition ! By site-specifically modifying microbial rhodopsin on live cell surface with organic fluorophores ...
New Year and New Students! 01 Jan,2018 As 2018 approaches, we are delighted to welcome three CCME graduate students to join our group: Yuxin Fang, Shuzhang Liu, and Ruixuan Wang. ...
Congratulations to Our Undergraduates! 01 Jan,2018 Congratulations to Yu Wang and three Yuxin's (~ Fang, ~ Mi, ~ Duan) for successfully defending their theses and getting Bachelor's degrees! ...
State-of-the-Art in Voltage Imaging 01 Jan,2018 The past decade has seen a proliferation of fluorescent voltage indicators. ...
Welcome to Ruirui and Yuxin! 01 Jan,2018 We are delighted to have Ruirui Ma and Yuxin Fang joining our group. ...
来年はピッチャー補強しないと‼️
球団自体が巨人ファのセリーグじゃ王様だけど所詮は裸の王様だったなぁ。
格の違いとはこういう事を言うのですね。
補強どれだけやれば¨
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Welcome to Zou Lab
Welcome to our lab at College of Chemistry and Molecular Engineering, Peking University!
We aim to invent chemical and biophysical tools to probe neuronal structure and activity at high spatial and temporal resolutions. We apply these tools to investigate the underlying physical forces, chemical signaling, and biological macromolecules that give rise to neuronal functions. Examples are fluorescent sensors, engineered enzymes, custom-built microscopes and software, etc.
Our methods are drawing from a wide range of techniques, including Biophysics, Protein engineering, Molecular Biology, Chemical Synthesis, Fluorescence Microscopy and Quantitative Modeling.
Current research projects include:
Optical mapping of action potential waveforms with genetically-encoded voltage indicators
Chemical labeling technique for mapping the localization of biomolecules in living cells
Proximity tagging methods for profiling synaptic protein synthesis
Selected PublicationsMore
Bright and fast multicoloured voltage reporters via electrochromic FRET
P. Zou†, Y. Zhao† et al.
Nat. Commun. (2014)
Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging
H. W. Rhee†, P. Zou† et al.
Science (2013)
Voltage imaging with genetically encoded indicators
Y. Xu, P. Zou#, and A. E. Cohen#
Curr. Opin. Chem. Biol. (2017)
Genetically-encoded voltage indicators
L. Peng†, Y. Xu†, and P. Zou
Chin. Chem. Lett. (2017)
Recent NewsMore
Hybrid is better!
01 Jan,2018
Our work on hybrid voltage indicator is officially accepted in Angewandte Chemie International Edition ! By site-specifically modifying microbial rhodopsin on live cell surface with organic fluorophores ...
New Year and New Students!
01 Jan,2018
As 2018 approaches, we are delighted to welcome three CCME graduate students to join our group: Yuxin Fang, Shuzhang Liu, and Ruixuan Wang. ...
Congratulations to Our Undergraduates!
01 Jan,2018
Congratulations to Yu Wang and three Yuxin's (~ Fang, ~ Mi, ~ Duan) for successfully defending their theses and getting Bachelor's degrees! ...
State-of-the-Art in Voltage Imaging
01 Jan,2018
The past decade has seen a proliferation of fluorescent voltage indicators. ...
Welcome to Ruirui and Yuxin!
01 Jan,2018
We are delighted to have Ruirui Ma and Yuxin Fang joining our group. ...
Lab Meeting: 7:00PM, Tuesday
A613, College of Chemistry
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About Us
Room A319, College of Chemistry and Molecular Engineering,
Peking University, Beijing, 100871, China
Tel: +86-10-6274-5395
Email: zoupeng@pku.edu.cn
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同名でも全然違う世界のZOU研究所があるようです。。
>遺伝的にエンコードされた電圧インジケーターによる活動電位波形の光学マッピング
>生細胞内の生体分子の局在をマッピングするための化学的標識技術
>シナプスタンパク質合成をプロファイリングするための近接タグ付け方法