MS96-8279 (1 slide) KIDNEY
Clinical: 59 year old man with a 9cm tan/brown renal mass.
DX: Renal cell carcinoma, granular cell type, nuclear grade 2 of 4
Confined to kidney, no lvs inv, margins free, tumor size 9.0 cms
Comment: The pure granular cell variant accounts for 7% of renal cell carcinomas. Cells with eosinophilic granular cytoplasm are often a component of higher grade clear cell rcca. Granular cell carcinomas tend to be o higher nuclear grade than clear cell renal cell ca. They behave and are treated identically stage for stage.
Grossly, the mitochondria-rich cells impart a brown color to the tumor.
(if these nuclei had more prominent nucleoli, it could easily pass for a grade 3 lesion)
Clinical: 59 year old man with a 9cm tan/brown renal mass.
DX: Renal cell carcinoma, granular cell type, nuclear grade 2 of 4
Confined to kidney, no lvs inv, margins free, tumor size 9.0 cms
Comment: The pure granular cell variant accounts for 7% of renal cell carcinomas. Cells with eosinophilic granular cytoplasm are often a component of higher grade clear cell rcca. Granular cell carcinomas tend to be o higher nuclear grade than clear cell renal cell ca. They behave and are treated identically stage for stage.
Grossly, the mitochondria-rich cells impart a brown color to the tumor.
(if these nuclei had more prominent nucleoli, it could easily pass for a grade 3 lesion)
