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news20100820gdn1

2010-08-20 14:55:43 | Weblog
[News] from [guardian.co.uk]

[guardian.co.uk > Environment > BP oil spill]

BP oil spill: US scientist retracts assurances over success of cleanup
NOAA's Bill Lehr says three-quarters of the oil that gushed from the Deepwater Horizon rig is still in the Gulf environment while scientists identify 22-mile plume in ocean depths

Suzanne Goldenberg, US environment correspondent
guardian.co.uk, Thursday 19 August 2010 21.34 BST
Article history


{Bill Lehr, a senior scientist at the NOAA, appeared before Congress to repudiate an earlier report he wrote, which suggested the majority of the oil had been captured. Photograph: Chip Somodevilla/Getty Images}

White House claims that the worst of the BP oil spill was over were undermined yesterday when a senior government scientist said three-quarters of the oil was still in the Gulf environment and a research study detected a 22-mile plume of oil in the ocean depths.

Bill Lehr, a senior scientist at the National Oceanographic and Atmospheric Administration (NOAA) departed from an official report from two weeks ago which suggested the majority of the oil had been captured or broken down.

"I would say most of that is still in the environment," Lehr, the lead author of the report, told the house energy and commerce committee.

The growing evidence that the White House painted an overly optimistic picture when officials claimed two weeks ago the remaining oil in the Gulf was rapidly breaking down fuelled a sense of outrage in the scientific community that government agencies are hiding data and spinning the science of the oil spill. No new oil has entered the Gulf since 15 July, but officials said yesterday the well is unlikely to be sealed for good until mid-September.

Under questioning from the committee chair, Ed Markey, Lehr revised down the amount of oil that went into the Gulf to 4.1m barrels, from an earlier estimate of 4.9m, noting that 800,000 barrels were siphoned off directly from the well.

By some estimates, as much as 90% of the oil was unaccounted for. Lehr said 6% was burned and 4% was skimmed but he could not be confident of numbers for the amount collected from beaches.

The NOAA has been under fire from independent scientists and Congress for its conclusions and for failing to explain how it arrived at its calculations. The agency has failed to respond to repeated requests from Congress to reveal its raw data and methodology.

Markey told Lehr the agency report had given the public a false sense of confidence. "You shouldn't have released it until you knew it was right," he said.

"People want to believe that everything is OK and I think this report and the way it is being discussed is giving many people a false sense of confidence regarding the state of the Gulf," Markey said.

Lehr said the agency would release all supporting data in two months.

But the impression of stonewalling has damaged the credibility of the Obama administration in the scientific community.

"That report was not science," said Ian MacDonald, an ocean scientist at Florida State University who has studied the Gulf for 30 years. He accused the White House of making "sweeping and largely unsupported" claims that three-quarters of the oil in the Gulf was gone.

"I believe this report is misleading," he said. "The imprint will be there in the Gulf of Mexico for the rest of my life. It is not gone and it will not go away quickly."

MacDonald went on to warn of a tipping point from which the wildlife and ecosystem in the Gulf could not recover.

Meanwhile, in the Science article, experts from the Woods Hole Oceanographic Institute mapped a 22-mile plume of oil droplets from BP's well, providing the strongest evidence so far over the fate of the crude.

"These results indicate that efforts to book-keep where the oil went must now include this plume," said Christopher Reddy, one of the Woods Hole team. The report also said the plume was very slow to break down by natural forces.

"Many people speculated that subsurface oil droplets were being easily degraded," said Richard Camilli, the lead author of the paper. "Well, we didn't find that. We found it was still there."

The scientists zig-zagged for hundreds of miles across the ocean to track the plume, taking 57,000 readings of its chemical signature during a 10-day research voyage at the end of June.

The Woods Hole effort reinforces earlier reports from research voyages by scientists from the University of Georgia and Texas A&M University who detected the presence of deepwater plumes of oil.

This week, University of South Florida scientists reported oil in amounts that were toxic to critical plankton on the ocean floor far east of the spill. Those findings have not been reviewed by other scientists.

According to the Woods Hole findings, the deepwater plume is 22 miles long – or about the length of Manhattan – 1.2 miles wide and 650ft high. It noted that the plume was not made up of pure oil but included toxic oil compounds including benzene and xylene.

Yesterday's testimony and the Science article put the White House and government scientific agencies increasingly out of step with independent scientists.

It also raises new questions about the administration's decision to use nearly 2m gallons of a chemical dispersant Corexit to break up the oil.

The NOAA chief Jane Lubchenco, herself an ocean scientist, had played down the first reports of oil in the ocean depths. MacDonald and other scientists have accused NOAA of discouraging them from making public their findings about lingering oil in the deepwater.

A NOAA spokeswoman said last night that the Woods Hole voyage was in late June, while the broken BP well was still spewing oil. "It's not necessarily an indication of where we are today" she said.

A NOAA team reported two weeks ago that just over a quarter of oil remained in the Gulf as a light sheen on the surface or degraded tar balls washing ashore.


[guardian.co.uk > Environment > Climate change]

Rising temperatures reducing ability of plants to absorb carbon, study warns
Research shows warming over past decade caused droughts that reduced number of plants available to soak up carbon dioxide

Alok Jha
guardian.co.uk, Thursday 19 August 2010 19.19 BST
Article history


{Droughts have wiped out plants that would have absorbed the carbon equivalent of all the man-made greenhouse gas emissions from the UK every year. Photograph: Patrick Pleul/EPA}

Rising temperatures in the past decade have reduced the ability of the world's plants to soak up carbon from the atmosphere, scientists said today.

Large-scale droughts have wiped out plants that would have otherwise absorbed an amount of carbon equivalent to Britain's annual man-made greenhouse gas emissions.

Scientists measure the amount of atmospheric carbon dioxide absorbed by plants and turned into biomass as a quantity known as the net primary production. NPP increased from 1982 to 1999 as temperatures rose and there was more solar radiation.

But the period from 2000 to 2009 reverses that trend – surprising some scientists. Maosheng Zhao and Steven Running of the University of Montana estimate that there has been a global reduction in NPP of 0.55 gigatonnes (Gt). In comparison, the UK's contribution to annual worldwide carbon dioxide emissions was 0.56Gt in 2007, while global aviation industry made up around 0.88Gt (3%) of the world total of 29.3Gt that year, according to UN data.

The researchers used data from the moderate resolution imaging spectroradiometer (Modis) on board Nasa's Terra satellite, combined with global climate data to measure the change in global NPP over the past decade.

"The past decade has been the warmest since instrumental measurements began, which could imply continued increases in NPP," wrote Zhao and Running in the journal Science.

But instead of helping plants grow, these rising temperatures instead caused droughts and water stresses, particularly in the southern hemisphere and in rainforests, which contain most of the world's plant biomass. The growth there has been curtailed by lack of water and increased respiration, which returns carbon to the atmosphere. These problems counteracted any increases in NPP seen at the high latitudes and elevations in the northern hemisphere.

Reduced plant matter not only reduces the world's natural ability to manage carbon dioxide in the atmosphere but could also lead to problems with growing more crops to feed rising populations or make sustainable biofuels.

"Under a changing climate, severe regional droughts have become more frequent, a trend expected to continue for the foreseeable future," said the researchers. "The warming-associated heat and drought not only decrease NPP, but also may trigger many more ecosystem disturbances, releasing carbon to the atmosphere. Reduced NPP potentially threatens global food security and future biofuel production and weakens the terrestrial carbon sink."

The researchers conclude that further monitoring will be needed to confirm whether the decrease in NPP they have observed in the past decade is an anomaly or whether it signals a turning point to a future decline in the world's ability to sequester carbon dioxide.

• This article was amended on 20 August 2010. The original referred to carbon dioxide as CO2 and CO². This has been corrected.

news20100820gdn2

2010-08-20 14:44:05 | Weblog
[News] from [guardian.co.uk]

[guardian.co.uk > Environment > Marine life]

More than 50 whales die after being washed up on New Zealand beach
Rescue volunteers continue efforts to save surviving pilot whales, which are described as being in 'fairly poor condition'

Associated Press
guardian.co.uk, Friday 20 August 2010 11.39 BST
Article history


{Rescuers try to save surviving whales after mass stranding in New Zealand}

Fifty-eight pilot whales have died after they were washed up on to an isolated beach in northern New Zealand. Rescue volunteers' initial efforts to refloat 15 others that survived failed earlier today.

A fresh attempt to save the 15 beached mammals – which weigh up to 1,500kg (3,300lb) each – will be made early on Saturday, using machinery including a crane and transporter, said Department of Conservation acting area manager Mike Davies.

The 73 pilot whales were probably stranded during the night on remote Karikari Beach which is why so many died before they were discovered, said the department's community relations manager, Carolyn Smith.

New Zealand frequently sees several mass whale strandings around its coastline, mainly each summer as whales pass by on their migration to and from Antarctic waters. Scientists have not been able to determine why whales become stranded.

A pod of 101 pilot whales were stranded on the same beach in 2007.

Kimberly Muncaster, chief executive of the Project Jonah whale aid group, said the 15 surviving whales were in "fairly poor condition".

About 40 people tried to refloat them at high tide on Friday. Among those helping the department were trained volunteers from the Far North Whale Rescue group.

Davies said the 15 whales would not need to be sedated for Saturday's second rescue attempt using the heavy equipment as they were already in quite a docile state.

"The plan at first light will be to remove the ... whales across about 1km of road by transporter and refloat them in (nearby) Matai Bay," he said, where sea conditions would be easier and the bay more sheltered.

New Zealand has one of the world's highest rates of whale strandings, according to the Department of Conservation. Since 1840, more than 5,000 strandings of whales and dolphins have been recorded around its coast.

[guardian.co.uk > World news > Pakistan flood]

Pakistan floods are a 'slow-motion tsunami' - Ban Ki-moon
UN general secretary urges countries to send more money, quicker as monsoon rains worsen flooding

Andrew Clark in New York and Allegra Stratton
guardian.co.uk, Thursday 19 August 2010 23.20 BST
Article history


{A Pakistani family stand on their farm compound surrounded by flood waters Photograph: Kevin Frayer/AP}

The United Nations general secretary, Ban Ki-moon, has appealed for swifter aid to provide immediate relief in food, shelter and clean water for the millions affected by the worst monsoon rains on record.

"Make no mistake, this is a global disaster," Ban told a hurriedly convened session of the UN general assembly. "Pakistan is facing a slow-motion tsunami. Its destructive powers will accumulate and grow with time," he warned.

Weather forecasts have said there could be four more weeks of rain, which will add to the flood problems.

The UN has appealed for $460m (£295m) in aid and donors have so far given about half that figure. But the secretary-general said all of the money was needed immediately to help victims over the next three months.

The US has pledged an extra $60m in help, bringing America's total aid to $150m.

In a video message, US secretary of state Hillary Clinton appealed to the American public to donate generously to a newly established "Pakistan relief fund".

"The enormity of this crisis is hard to fathom, the rain continues to fall and the extent of the devastation is still difficult to gauge," said Clinton. "Our thoughts and prayers are with those who have lost loved ones, those who have been displaced from their homes and those left without food and water."

The US special representative for Pakistan, Richard Holbrooke, said "many billions" would be needed to respond to the flooding. Speaking at the Asia Society in New York, he called on other countries, such as China, to step up to the plate and said: "The water has affected everyone, It's an equal opportunity disaster, and military operations have effectively faded away."

The British government yesterday pledged to double its emergency payments, raising its pledge to £64.3m.

Last weekend, one of the UK's funds for disasters – the CERF – was included in a list of items sent by DFID's director of policy to international development secretary Andrew Mitchell as possibly expendable. His department insists the list was only a speculative part of due process, since the department, like all others, is expected to consider value for money, despite DFID being ringfenced from cuts.

But tonight Mitchell, who has recently visited Pakistan to inspect the effect British aid has had so far, told the UN general assembly in New York that the international community had to do more. He told the UN it was "deeply depressing" that the international community was "only now waking up to the true scale of this disaster".

Mitchell will meet other development secretaries and push them to give more. He emphasised funding would only be allocated to NGOs and UN agencies which could prove they were helping people get back on their feet.

He highlighted a fund that would give farmers new seed to plant new crops to replace those destroyed by the floods as a project the UK would back.

He said: "I've come to New York directly from Pakistan, where I saw the dire need for more help. I saw the sheer and shocking magnitude of this catastrophe. It is clear that unless more aid is delivered now, many more people will die from disease and malnutrition. The UK is already helping more than three million people in flood-affected areas." This doubling of our aid should now provide water and sanitation to 500,000 people; shelter to 170,000 people; help meet the nutritional needs of 380,000 people and provide enough health services to cover a population of 2.4 million people."

news20100820nn1

2010-08-20 11:55:17 | Weblog
[naturenews] from [nature.com]

[nature.com > Nature News]

Published online 19 August 2010 | Nature | doi:10.1038/news.2010.420
News

Extent of lingering Gulf oil plume revealed
Extensive chemical analysis confirms that undegraded oil remains at ocean depths.

Amanda Mascarelli


{Oil from the Deepwater Horizon spill persists underwater.
CHRISTOPHER BERKEY/ EPA/Photoshot}

The swathe of oil still stretching from the Deepwater Horizon spill is over 35-kilometres long, according to a new report. The study, published in Science1, is the first major peer-reviewed analysis of the underwater oil plume. It also indicates that the plume has persisted for several months, with oxygen measurements showing little sign of the oil being degraded quickly by microbes in the water.

A team led by researchers at the Woods Hole Oceanographic Institution (WHOI) in Massachusetts found that the main plume is suspended at a depth of 1,000–1,200 metres below the surface and in some places is more than 2 kilometres wide and 200 metres thick. Other oil plumes are present in the Gulf of Mexico, but this was the first to be identified and is the most thoroughly sampled.

"Up to this point, people had identified hydrocarbons in subsurface waters, but they weren't able to say just how wide the plume was, how tall it was, or how long it was, or that it was continuous," says lead author Richard Camilli, an oceanographer at the WHOI.

Beginning at the site of the blown-out oil pipe, Camilli and his colleagues studied the plume's properties by zigzagging an autonomous underwater vehicle (AUV) through the plume. They suspect that the plume was longer than 35 kilometres, but their measurements were stopped short in late June by the approach of Hurricane Alex. But between 19 June and 28 June, the team took more than 3,500 real-time measurements of hydrocarbon concentrations and tracked the presence of 10 chemicals in the water column by using a mass-spectrometer attached to the AUV. They made another 2,300 chemical measurements while sampling oxygen concentrations in the water using a device lowered down on a cable.

The team has a "technological capability that is second to none on this planet," says John Kessler, a chemical oceanographer at Texas A&M University in College Station. "They can basically swim the AUV like a fish through this plume, measuring all the different oil and gas hydrocarbons and do a much more efficient job of mapping the area of this plume than anyone else can."

Slow degradation

In contrast to the findings of other groups, the new report concludes that ocean oxygen levels have not dipped substantially in the region of the plume since the spill began and that little of the oil had degraded in the regions they sampled. Oil- and gas-consuming microbes are naturally present in the ocean, and consume oxygen as they break down hydrocarbons, making oxygen levels a good indicator of how quickly oil is being degraded.

"Our findings suggest that the microbial rate of degradation was relatively slow," says Benjamin Van Mooy, an oceanographer at the WHOI and a co-author of the study. "What that would mean is it would take quite a long time before we got to the low oxygen levels that might be harmful to animals." But that would also mean that the plume will not disappear any time soon.

In some cases, the group found lower-than-normal oxygen levels, but they attributed this to flawed instrumentation. Oxygen sensors can become fouled by oil; when the team used a backup method known as Winkler titration, which allows oxygen concentrations to be measured precisely, they could not reproduce the low oxygen values in some cases.

But Kessler's group, which sampled the same plume as the WHOI team earlier in June, reported oxygen depletions of up to 30%, indicating that biodegradation was occurring quickly. Another team found that oxygen concentrations were 30–50% lower than normal in some places along the plume's path. And both of these teams reproduced their own findings by using independent methods (see 'Muddying the waters on Gulf oxygen data').

Both situations could be occurring within the plume, says Kessler. Camilli's team "could be sampling in areas that just haven't witnessed those sorts of oxygen reductions, whereas we have sampled in areas that had a slightly different hydrocarbon soup mixture".

Oil buffet

David Valentine, a geomicrobiologist at the University of California, Santa Barbara, who was on the same vessel as Kessler, says that microbial respiration rates are likely to vary with location and maturity of the plume. Valentine compares this to a buffet: "You put out something people actually like, such as a filet mignon, and that's going to go quickly. But your stale nachos at your taco bar, they're still going to be there."

But Valentine disagrees with the conclusion that the respiration rates reported in the study indicate slow metabolism. "That's a very fast rate for something happening at those kinds of depths," says Valentine.

The initial reports of oil and gases were lingering deep in the water rather than rising to the surface (see 'Oil cruise finds deep-sea plume') came as a shock to many scientists. Oil on the surface is relatively easy to clean up, whereas hydrocarbons that lurk deep underwater could expose marine organisms to their toxic effects for much longer.

Among the chemicals that Camilli's team measured were benzene, toluene, ethylbenzene and xylenes, collectively called BTEX. These light-weight volatile organic compounds (VOCs) are typically the first molecules to evaporate from oil at the ocean surface. It is unclear how long they might linger in the water column. "VOCs are considered to be acutely toxic but short-lived in most oil spill situations," says Judy McDowell, a physiological ecologist at the WHOI. "In this instance, for BTEX to persist at depth would suggest that acute toxic effects would occur."

Another group of researchers, from the University of South Florida in St Petersburg, has preliminary evidence that phytoplankton and bacteria are being exposed to toxic concentrations of chemicals northeast of the ruptured oil pipe.

But researchers cannot say exactly which ingredients remain in the toxic soup of the plume or how they might affect ocean creatures. "It's very hard right now to get any handle as to the total inventory in the plume," says Christopher Reddy, a co-author of the study who is also based at the WHOI. Oil has thousands of components which behave differently from each other in water. Some of the breakdown products of oil and gases might have risen to the surface, whereas others are still trapped in the plume, Reddy says. "We'll probably know in a month or so when we get a much better, fuller data set."

The WHOI researchers note that their sampling was a "snapshot" in time, and that the plume has probably changed since late June. In fact, researchers are not currently sure of the whereabouts of the plume, according to Valentine.

"I think that we're going to see that many of the hydrocarbons in these oil plumes are going to be spinning around the Gulf, probably staying around the same depth range for some time to come, certainly months, if not years," says Valentine.

References
1. Camilli, R. et al. Science advance online publication doi:10.1126/science.1195223 (2010).

news20100820nn2

2010-08-20 11:44:27 | Weblog
[naturenews] from [nature.com]

[nature.com > Nature News]

Published online 19 August 2010 | Nature | doi:10.1038/news.2010.418
News

Earth's green carbon sink on the wane
Satellite data indicate that carbon storage by plants is decreasing despite climate warming.

Rhiannon Smith


{Is one of the world's largest carbon sinks filling up?
ymgerman/iStockphoto}

The capacity of plants to act as a carbon sink could be on the decline.

As global temperatures have risen in recent decades, the amount of atmospheric carbon being converted into plant biomass has increased in step. However, in a paper published today in Science, ecologists Maosheng Zhao and Steve Running at the University of Montana in Missoula report a surprising reversal of this trend over the last decade, despite its having been the warmest on record1.

In 2003, a study on which Running was a co-author, led by Ramakrishna Nemani, who is also at the University of Montana, reported an increase in plant productivity between 1982 and 1999. The researchers attributed that trend to a warmer climate and increased solar radiation2. Zhao and Running expected to find a similar increase for 2000-2009 — an expectation that was not met.

Along with the oceans, plants are doing us a great service by taking up about half of all fossil-fuel carbon dioxide emissions from the atmosphere, says Running. "This is the first indication that it might be slipping."

The duo analysed visible and infra-red spectrum data from the Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA's Terra satellite to distinguish different plant ecosystems and to measure the density of the vegetation. They then examined factors that influence plant growth, such as water availability and day length, to estimate the amount of atmospheric carbon accumulated as plant biomass — the Net Primary Production (NPP).

The results show that carbon uptake by plants did increase in some areas — primarily in the Northern Hemisphere — including parts of North America, western Europe, India and China. But in areas where carbon uptake decreased, the drop was sharp. In the Southern Hemisphere, 70% of plant-covered land, including regions of South America, Africa and Australia, showed a decrease in NPP.

"On balance," Running says of carbon uptake by plants, "when you add up all the pluses and minuses, there is a decrease".

Over the limit

The researchers say that this fall in global carbon uptake can be attributed to regional droughts, such as the severe drought in the Amazon in 2005, and a general drying trend in the Southern Hemisphere that has worsened with global warming.

Why the Northern and Southern Hemispheres have responded differently to warmer climates and increased drought is unclear. Running suggests that the variations could be attributable to the different constraints faced by plants on opposite sides of the Equator. In the Northern Hemisphere, the limiting factor for plant growth tends to be temperature and the length of the growing season — both of which have increased with global warming. The main limitation on plant growth in the Southern Hemisphere, meanwhile, is water availability — which is why droughts have had a greater impact there.

Michael Crimmins, a climatologist at the University of Arizona in Tucson, says that "this paper does a nice job" of highlighting areas of the planet where plant growth is limited by the availability of water, rather than by temperature. "I'm glad to finally see some global-scale evidence that a warmer world is not necessarily a greener world," he says.

However, Bill Munger, an ecologist at Harvard University in Cambridge, Massachusetts, is critical of the methods used in the paper. "The type of modelling they used is good at highlighting spatial patterns in vegetation processes, but very dependent on assumed influence of moisture and temperature," he says.

Running agrees that they had to make some assumptions. "I fully acknowledge that when you're making global-level calculations you're seeing only a very small part of the activity of the ecosystem and inferring the rest," he says.

"Until we see another 10–20 years of data, it would be premature to guarantee that this is a permanent trend, but it certainly means that we'd better be watching this really carefully," he adds.

References
1. Zhao, M. & Running, S. W. Science 329, 940-943 (2010). | Article | ChemPort |
2. Nemani, R. R. et al. Science 300, 1560-1563 (2003). | Article | PubMed | ChemPort |

news20100820nn3

2010-08-20 11:33:04 | Weblog
[naturenews] from [nature.com]

[nature.com > Nature News]

Published online 19 August 2010 | Nature | doi:10.1038/news.2010.419
News

Drug flexes muscle against cancer
Decoy protein helps to fight cancer in mice by stopping muscle breakdown.

Alla Katsnelson


{There are few treatments for the muscle loss that accompanies cancer.
Sebastien Bergeron / iStockphoto}

Researchers have created a molecule that, in mice, can fully reverse the devastating muscle loss that often accompanies advanced cancer — and thereby increase the lifespan of animals with the disease.

The molecule blocks the activity of a key muscle-limiting protein called myostatin by acting as a decoy. Instead of myostatin binding to its normal receptor and triggering muscle wastage, it is 'mopped up' by binding to the decoy molecule instead.

Muscle wasting — called cachexia — is thought to account for about 30% of deaths in patients with cancer, but how exactly cachexia is spurred by cancer — or indeed exactly how it leads to a patient's decline — isn't known. It is thought that several molecular pathways work in tandem, "activating an axis of evil to control muscle mass in a negative way", says H. Q. Han, lead author of the study and scientific director of the metabolic disorders division at Amgen, a biotechnology company in Thousand Oaks, California.

Han and his group wanted to find the dominant pathway responsible for cancer cachexia, and then design a way to block it in order to treat patients. Several studies have shown that blocking the myostatin pathway can promote muscle growth, says Han, and some have shown that a molecule closely related to myostatin, called activin A, becomes more abundant in patients with some cancers.

"We examined a large random collection of cancer cell lines in vitro, and found that one-third of them secreted large amounts of activin A," says Han. "This led us to believe that activin A must have some systemic function when overproduced in a cancer setting."

Muscling in

The researchers created a soluble version of the activin A receptor — which is thought to affect both myostatin and activin A signalling — by fusing a piece of human activin receptor to an antibody. This decoy mopped up the ligands that usually bind to the real receptor, thus blocking receptor activation.

{“There's really an overwhelming amount of data now showing the benefits of targeting this pathway.”}

A single injection of the soluble receptor into normal mice boosted their muscle mass by 25% or more in a week or two. When it was given to mice implanted with colon cancer cells, their muscle mass returned to normal, even though their tumours continued to grow. Strikingly, all of the animals that did not receive the soluble receptor were dead 40 days after cancer cells were implanted, but more than half of the treated animals survived to this point. The study will be published tomorrow in the journal Cell1.

Han's group isn't the first to try to manipulate the myostatin pathway to treat muscle wasting. "There's really an overwhelming amount of data now showing the benefits of targeting this pathway," says Se-Jin Lee, a molecular biologist at Johns Hopkins University in Baltimore, Maryland, who co-discovered the myostatin gene and its role in regulating skeletal muscle mass in 19972.

The fact that disrupting the myostatin pathway caused such strong muscle regrowth isn't so surprising, says Lee, because other studies have shown that this pathway has an extremely negative effect on muscle growth.

Ken Fearon, a surgical oncologist at the University of Edinburgh, UK, who has studied cancer cachexia, agrees. "They've antagonized one of the main in vivo brakes" to muscle growth, he says. "If you take the brakes off a car, it'll keep going down the road."

Limited options

What is most exciting is that the treatment prolonged survival, according to Lee and Fearon, because few treatments for cancer cachexia currently exist. "The reason that oncologists don't bother measuring — let alone treating — cachexia is that they feel their options are so limited outside of treating the cancer," Fearon says.

Despite the molecule's powerful effect in mice, "does blocking this pathway in humans also cause muscle to grow?" asks Lee. "That question has not been answered yet."

It is also still unclear whether the myostatin pathway plays a causative role in regulating the condition, he says, and the study doesn't provide all the answers. "The fact that you can prevent the muscle loss doesn't say that it's due to overactivity in this pathway," he notes.

Several pharmaceutical and biotech companies have begun clinical trials to test compounds that target the myostatin pathway. In the only such study published so far, researchers from Johns Hopkins University and drug firm Wyeth (now part of Pfizer) used an antibody to block myostatin in an attempt to treat the muscle-wasting disease muscular dystrophy3. "Those results were quite wishy-washy," Lee says.

Other trials, including on testing a similar form of the soluble activin A receptor by pharmaceutical company Acceleron, based in Cambridge, Massachusetts, are still in progress. Unlike many of the other compounds being tested, says Lee, this particular compound can bind not just to myostatin and activin but also to many other related molecules. This could make it more potent, he notes, "but of course it might also be the downfall" if this lack of specificity leads to unwanted side effects in patients.

References
1. Zhou, X. et al. Cell 142, 531-543 (2010).
2. McPherron, A. C. et al. Nature 387, 83-90 (1997). | Article
3. Wagner, K. R. et al. Ann. Neurol. 63, 561-571 (2008). | Article

news20100820bg1

2010-08-20 10:55:03 | Weblog
[News] from [businessgreen.com]

[BusinessGreen.com > News > Politics]

Australians go to the polls as climate policy hangs in balance
Prime Minister Julia Gillard makes last-ditch carbon trading pledge as polls show election is too close to calll

Jessica Shankleman, BusinessGreen, 20 Aug 2010


The future direction of Australia's climate change policy is hanging in the balance as the country prepares to the polls in its knife edge federal election tomorrow.

The latest poll shows rival Labor and Coalition parties tied on 50 per cent of the vote, with Labor's primary vote dropping three percentage points and the Coalition's rising by the same amount, according to a Newspoll survey for The Australian.

Controversial plans for a national carbon trading scheme have remained a hot topic throughout the election after previous Prime Minister Kevin Rudd was forced to resign in June following his repeated failure to pass promised climate change legislation.

Rudd's replcement, incumbent Labor Prime Minister Julia Gillard, today sent a clear signal that she would move to introduce a price on carbon if re-elected.

Speaking to The Australian, Gillard promised to legislate in order to impose a carbon price during the next term, if Labor forms the next government and has sufficient support from legislative partners such as the Green Party.

"I don't rule out the possibility of legislating a Carbon Pollution Reduction Scheme, a market-based mechanism, I rule out a carbon tax," she told the paper.

Meanwhile, Gillard's rival, Liberal leader Tony Abbott, has consistently ruled out introducing a price on carbon, stating that even if the international community agreed on a carbon price, a government led by him would not necessarily back it.

A surprising winner in the election, however, looks set to be the fast growing Greens, with polls suggesting the party could secure 14 per cent of the vote, almost doubling its performance in the 2007 election.

"It is increasingly evident that neither the Prime Minister nor Mr Abbott has the courage to do what is needed on climate change," said Greens deputy leader Senator Christine Milne in a statement. "This is why the community needs more Greens in parliament, and in balance of power in the senate, to be the strongest possible voice for action on climate change."

The contest has already recorded record numbers of early voters, according to the Electoral Commission, with around 1.8 million votes cast so far, representing about 12.5 per cent of all people enrolled to vote.


[BusinessGreen.com > News > Offsets]

Forestry Commission launches carbon offset standard
New Woodland Carbon Code to offer reassurance that tree-planting projects really sequester carbon

James Murray, BusinessGreen, 20 Aug 2010


The Forestry Commission is set to begin testing a new quality assurance scheme for carbon offsetting projects in the UK designed to ensure that tree-planting initiatives really deliver promised cuts in carbon emissions.

The new Woodland Carbon Code has been developed in conjunction with scientists, forestry experts and project developers and was finalized earlier this year following a consultation period.

The Commission is now starting a six month long testing programme using 12 pilot projects that aims to refine the code ahead of its formal launch next year.

Tim Rollinson, Forestry Commission Director-General, said the new code would give businesses buying carbon credits from British tree-planting projects greater confidence that they are funding quantifiable emission reductions.

"There are now many commercial schemes that encourage individuals and businesses to contribute to tree planting to help compensate for their carbon footprint," he said. "But before investing in projects people want to know that schemes will actually deliver what they claim. The Woodland Carbon Code will provide that reassurance and will encourage more investment in tree planting in the UK."

A spokesman for the Commission admitted that there had been concerns that some projects had over-stated the level of emission reductions they deliver – a problem that should be addressed through the new code.

He explained that projects that qualify for the code will be required to comply with a scientific methodology that measures how much carbon specific tree-planting projects sequester.

They also have to demonstrate that the project would not have gone ahead without funding from offset credits and meet sustainability requirements designed to ensure that the trees that are planted will remain in place.

The move comes as new research published in the journal Science this week raised worrying questions about plants ability to continue to soak up carbon dioxide as temperatures rise.

The study from Maosheng Zhao and Steven Running of the University of Montana suggested that large scale droughts over the past decade had reduced the amount of carbon dioxide absorbed and stored by plants and forests.

The findings will come as a surprise to some scientists who haad predicted the increases in average global temperatures will help to stimulate plant growth.

"Under a changing climate, severe regional droughts have become more frequent, a trend expected to continue for the foreseeable future," wrote the researchers. "The warming-associated heat and drought not only decrease NPP (net primary production), but also may trigger many more ecosystem disturbances, releasing carbon to the atmosphere. Reduced NPP potentially threatens global food security and future biofuel production and weakens the terrestrial carbon sink."


[BusinessGreen.com > News > Renewables]

Yingli beats expectations with solid quarter
But share price still slips on concerns over 2011 demand

BusinessGreen.com Staff, BusinessGreen, 20 Aug 2010


Chinese solar firm Yingli Green Energy Holding Co posted better than expected second quarter results yesterday, but still saw its share price fall as concerns over projected demand during 2011 continued to stalk the market.

The company, which has risen to prominence in recent months after funding a multi-million dollar advertising campaign at the World Cup in South Africa, its second quarter gross margins reached a record 33.5 per cent while revenues climbed 80 per cent year-on-year to $398.1m.

The performance comfortably outstripped analyst earning predictions that the company's margins would hover between 28 and 30 per cent.

Liansheng Miao, chairman and chief executive at Yingli Green Energy, said that the company was rapidly building a global presence.

"In Europe, we are fully stretched to satisfy our existing customer base and to continue to attract new customers in high growth emerging markets such as France, Italy, Czech Republic, Greece and the United Kingdom," he said. "In North America, our sales network has expanded into 18 states in the US, as well as Canada and the Caribbean, and we have become the leading supplier of PV modules in New Jersey and California."

But despite the strong performance the company's share price slipped by around three per cent after company executives admitted that average selling process for solar technologies could fall by "high single digits" in percentage terms.

Across the industry manufacturers are concerned that plans to scale back solar incentives in key markets such as Germany, Spain and Italy could lead to a slowing in demand that will in turn drive down prices.

In related news, British silicon wafer supplier PV Crystalox Solar saw its share price fall 10 per cent yesterday after the company reported that a slump in the global price of silicon wafers had resulted in its half year earnings more than halving year-on-year to €12.4m.

The company attempted to put a positive spin on the figures, noting that it had delivered a sizable increase in shipments during the first half of the year that it expects to continue for the rest of 2010. However, it also admitted that wafer prices could continue to come under pressure as a result of growing competition from China.

news20100820bg2

2010-08-20 10:44:12 | Weblog
[News] from [businessgreen.com]

[BusinessGreen.com > News > Risk]

BP oil spill: US scientist retracts assurances over success of cleanup
NOAA's Bill Lehr says three-quarters of the oil that gushed from the Deepwater Horizon rig is still in the Gulf environment while scientists identify 22-mile plume in ocean depths

Suzanne Goldenberg, The Guardian - Published under license by, BusinessGreen, 20 Aug 2010


White House claims that the worst of the BP oil spill was over were undermined yesterday when a senior government scientist said three-quarters of the oil was still in the Gulf environment and a research study detected a 22-mile plume of oil in the ocean depths.

Bill Lehr, a senior scientist at the National Oceanographic and Atmospheric Administration (NOAA) departed from an official report from two weeks ago which suggested the majority of the oil had been captured or broken down.

"I would say most of that is still in the environment," Lehr, the lead author of the report, told the house energy and commerce committee.

The growing evidence that the White House painted an overly optimistic picture when officials claimed two weeks ago the remaining oil in the Gulf was rapidly breaking down fuelled a sense of outrage in the scientific community that government agencies are hiding data and spinning the science of the oil spill. No new oil has entered the Gulf since 15 July, but officials said yesterday the well is unlikely to be sealed for good until mid-September.

Under questioning from the committee chair, Ed Markey, Lehr revised down the amount of oil that went into the Gulf to 4.1m barrels, from an earlier estimate of 4.9m, noting that 800,000 barrels were siphoned off directly from the well.

By some estimates, as much as 90 per cent of the oil was unaccounted for. Lehr said six per cent was burned and four per cent was skimmed but he could not be confident of numbers for the amount collected from beaches.

The NOAA has been under fire from independent scientists and Congress for its conclusions and for failing to explain how it arrived at its calculations. The agency has failed to respond to repeated requests from Congress to reveal its raw data and methodology.

Markey told Lehr the agency report had given the public a false sense of confidence. "You shouldn't have released it until you knew it was right," he said.

"People want to believe that everything is OK and I think this report and the way it is being discussed is giving many people a false sense of confidence regarding the state of the Gulf," Markey said.

Lehr said the agency would release all supporting data in two months.

But the impression of stonewalling has damaged the credibility of the Obama administration in the scientific community.

"That report was not science," said Ian MacDonald, an ocean scientist at Florida State University who has studied the Gulf for 30 years. He accused the White House of making "sweeping and largely unsupported" claims that three-quarters of the oil in the Gulf was gone.

"I believe this report is misleading," he said. "The imprint will be there in the Gulf of Mexico for the rest of my life. It is not gone and it will not go away quickly."

MacDonald went on to warn of a tipping point from which the wildlife and ecosystem in the Gulf could not recover.

Meanwhile, in the Science article, experts from the Woods Hole Oceanographic Institute mapped a 22-mile plume of oil droplets from BP's well, providing the strongest evidence so far over the fate of the crude.

"These results indicate that efforts to book-keep where the oil went must now include this plume," said Christopher Reddy, one of the Woods Hole team. The report also said the plume was very slow to break down by natural forces.

"Many people speculated that subsurface oil droplets were being easily degraded," said Richard Camilli, the lead author of the paper. "Well, we didn't find that. We found it was still there."

The scientists zig-zagged for hundreds of miles across the ocean to track the plume, taking 57,000 readings of its chemical signature during a 10-day research voyage at the end of June.

The Woods Hole effort reinforces earlier reports from research voyages by scientists from the University of Georgia and Texas A&M University who detected the presence of deepwater plumes of oil.

This week, University of South Florida scientists reported oil in amounts that were toxic to critical plankton on the ocean floor far east of the spill. Those findings have not been reviewed by other scientists.

According to the Woods Hole findings, the deepwater plume is 22 miles long – or about the length of Manhattan – 1.2 miles wide and 650ft high. It noted that the plume was not made up of pure oil but included toxic oil compounds including benzene and xylene.

Yesterday's testimony and the Science article put the White House and government scientific agencies increasingly out of step with independent scientists.

It also raises new questions about the administration's decision to use nearly two million gallons of a chemical dispersant Corexit to break up the oil.

The NOAA chief Jane Lubchenco, herself an ocean scientist, had played down the first reports of oil in the ocean depths. MacDonald and other scientists have accused NOAA of discouraging them from making public their findings about lingering oil in the deepwater.

A NOAA spokeswoman said last night that the Woods Hole voyage was in late June, while the broken BP well was still spewing oil. "It's not necessarily an indication of where we are today" she said.

A NOAA team reported two weeks ago that just over a quarter of oil remained in the Gulf as a light sheen on the surface or degraded tar balls washing ashore.


[BusinessGreen.com > News > Transport]

Mitsubishi drops electric vehicle price in readiness for sales war
Company slashes price of iMiev as it prepares to take on the Nissan Leaf

BusinessGreen.com Staff, BusinessGreen, 20 Aug 2010


The anticipated wave of new electric cars may still be months away from rolling out of UK showrooms, but the race to dominate the electric vehicle market is already hotting up after Mitsubishi announced yesterday that it has dropped the price of its upcoming iMiev.

The company said that it has slashed the launch price of the car from £38,699 to £28,990 for orders placed for delivery from January next year. The move follows in the wake of the government's decision to retain its proposed £5,000 incentive for motorists buying new electric cars, meaning customers will pay £23,990 for the iMiev.

The price cut brings the iMiev pretty much in line with Nissan's high-profile Leaf electric car, which is expected to be priced from £23,350 after the government's incentive.

A major sales battle is brewing ahead of the launch early next year of several electric cars from large manufacturers such as Mitsubishi and Nissan.

Mitsubishi is attempting to position its iMiev as the first to market, arguing that the car has a strong track record after a major testing programme that has seen 2,300 vehicles deployed on the road in Japan.

The company also revealed that it has already taken several UK orders for delivery in January and is expecting increased interest in the wake of the price cut.

"The i-Miev will remain first in all respects," said Mitsubishi Motors' UK managing director Lance Bradley. "We have been first in almost every aspect of the UK’s EV market for the past two to three years and we're not going to give up that position easily. The electric vehicle is now a reality, with all our cars being European Whole Type Vehicle Approved."

news20100820bg3

2010-08-20 10:33:24 | Weblog
[News] from [businessgreen.com]

[BusinessGreen.com > News > Incentives]

Japan plots new green stimulus package
Draft report reveals government is planning to increase support for clean tech manufacturers

BusinessGreen.com Staff, BusinessGreen, 20 Aug 2010


The Japanese government is reportedly preparing a major new economic stimulus package that will focus on driving investment in clean and energy efficient technologies.

According to reports in the Nikkei newspaper earlier today, the government has prepared a draft plan that would introduce new subsidies for factories developing green technologies, such as lithium ion batteries, LED lighting and other energy efficient and renewable energy products.

The plan, which is expected to be presented today by Economics Minister Satoshi Arai to recently-elected Prime Minister Naoto Kan, also proposes extending current subsidies supporting energy efficient consumer electronics and continuing with a home loan programme that promises fixed rate loans for energy efficient homes.

The stimulus package could be approved as early as next month as the government seeks to protect Japan's increasingly fragile recovery.

Recent data has suggested that the country's export-led recovery is slowing as the Yen continues to strengthen and the government is keen to intervene in order to avoid the threat of stagnation.

The bulk of the stimulus package is expected to focus on low carbon industries. However, it will also feature new services to help young people find jobs and increased support for small firms.


[BusinessGreen.com > News > Supply chain]

Global firms applaud new greenhouse gas yardsticks
More than 60 companies complete road testing of new global standards for measuring carbon footprint of products and supply chains

BusinessGreen.com staff, BusinessGreen, 20 Aug 2010


More than 60 leading global firms have finished testing two new greenhouse gas (GHG) reporting standards, taking industry a step closer to a universal approach for measuring and managing emissions.

Sixty-two firms from 17 countries, including household names such as 3M, Deutsche Telekom and IKEA, tested blueprints for two new GHG protocol reporting and accounting standards.

The first protocol, dubbed "Product Lifecycle", provides a standardised approach for measuring the greenhouse gas emissions associated with individual products, while the second protocol, known as "Scope 3 (Corporate Value Chain)" , covers emissions from a business's supply chain.

The standards were developed by the World Resources Institute (WRI) and the World Business Council for Sustainable Development (WBCSD), which said the new benchmarks should help firms and public sector organisations measure, analyse and manage GHG emissions through their wider value chains.

"Companies, policymakers and individuals are looking for ways to reduce their contribution to climate change, but do not always have the tools they need to make informed decisions," the partners said. "Increasingly, companies are looking beyond their own boundaries and developing strategies to reduce emissions in their supply chains and in the products they make and sell."

According to WRI and WBCSD, the majority of firms involved in the testing encountered little difficulty when using the protocols and were able to produce reports detailing their supply chain, or Scope 3, emissions.

Many of the companies in the trial said they would be willing to complete GHG emissions reports in line with the standards on an annual basis.

"We're really looking forward to having a standard that can be used globally, for communication across a broad range of stakeholders," said Robert ter Kuile, senior manager of energy and climate change at PepsiCo, one of the companies in the trial.

WRI and WBCSD now plan to revise the two blueprints, based on feedback from the firms, with a view to publishing the final standards by the end of this year.



[BusinessGreen.com > News > Offsets]

CER prices climb as UN steps up CDM probe in China
UN confirms four Chinese HFC emission reduction projects are now under investigation

Danny Bradbury, BusinessGreen, 20 Aug 2010


Prices of Clean Emissions Reduction (CER) carbon credits have hit a seven-week high, after the UN announced it is to review a number of Chinese projects participating in the Clean Development Mechanism (CDM) offsetting scheme.

The announcement places requests for CERs from four Chinese CDM projects producing hydrofluorocarbons (HFCs) under official review. The move follows criticism from green groups who said that a number of projects were deliberately generating greater levels of greenhouse gases so that they could destroy them and create saleable credits.

CER issuance requests from the Shandong Dongyue, Zhejiang Dongyang, China Fluoro and Changshu 3F Zhonghao New Chemical Materials Co projects will be reviewed by the UN. The investigation is likely to set back the issuance of the CERs to the projects by at least two months.

The announcement led to a rapid increase in the price of CERs as traders scrabbled to lay claim to what is set to become an increasingly scarce commodity.

The projects under review represent almost a quarter of the CDM-based projects dealing with the reduction of HFCs, and are the most lucrative of the HFC projects qualified under the CDM.

After the announcement, CER prices rose by 3.8 per cent, reaching a seven-week high. The spike in prices could be well founded – spokespeople at the UN suggested that the review could spread to other CER issuance requests from HFC-related projects in the Clean Development Mechanism.

Under the Kyoto Protocol's CDM initiative, emission reduction projects in the developing world can issue and sell CERs to industrialised nations.

However, groups such as CDM Watch have pointed to loopholes in the mechanism that potentially allow CDM qualifying projects to produce more pollutants than they need to, purely as a means of gaining more CERs that can then be monetis ed.

Criticisms have also been levelled at the Designated Operational Entities, commercial companies that inspect projects to be certified under the CDM. The WWF and German-based research body Oeko-Institut issued a report in June accusing some of the certification firms of failing to adequately check that projects have delivered real cuts in emissions.