なんくるないさ~、沖縄での研修医生活

臨床研修のメッカ沖縄にあって忙しさNo.1を自負する中部徳洲会病院。スーパー研修医がリレーでつづる研修医ブログ。

なぜ女性は男性より脂肪がつきやすいのか

2009-03-06 10:39:43 | Weblog
医学雑誌の速報版に興味深い報告を見つけました。
ホルモンの働きって複雑なんですね。
ちなみに、oestrogen = estrogen = エストロゲン(卵胞ホルモン、女性ホルモンの一種)

以下は引用です。速報の原文もつけておきます。
ダイエット外来 今西


------紹介記事(日本語)からの引用
なぜ女性は男性より脂肪がつきやすいのか
University of New South Walesの研究チームは女性ホルモンが脂肪の蓄積と妊娠に大きな影響を与えていることを初めて突き止めた。女性ホルモンの一種oestrogenは食後の脂肪燃焼を減少させ脂肪を蓄積しやすくする作用があることが分かった。この研究は『Obesity Reviews』に発表された。

------原文の引用
Public release date: 2-Mar-2009
Contact: Anthony O'Sullivan
a.osullivan@unsw.edu.au
61-413-165-562
University of New South Wales

Why do women store fat differently from men?

Evidence points to estrogen as the regulator of body fat
It's a paradox that has flummoxed women for generations – their apparent ability to store fat
more efficiently than men, despite eating proportionally fewer calories.
While it has long been suspected that female sex hormones are responsible, a University of New
South Wales (UNSW) research review has for the first time drawn a link between one hormone
– oestrogen – and its impact on fat storage for childbearing.

On average, women have 6 to 11 percent more body fat than men. Studies show oestrogen
reduces a woman's ability to burn energy after eating, resulting in more fat being stored around
the body. The likely reason is to prime women for childbearing, the review suggests.

"Female puberty and early pregnancy – times of increased oestrogen – could be seen as states
of efficient fat storage in preparation for fertility, foetal development and lactation," the study's
author Associate Professor Anthony O'Sullivan, from UNSW's St George Clinical School, said.

The findings, which appear in Obesity Reviews, the journal of the prestigious International
Association for the Study of Obesity, may have implications for dietary advice given to women
during pregnancy and the design of exercise regimes.

"From an energy balance point of view there is no explanation why women should be fatter than
men, particularly since men consume more calories proportionately," Associate Professor
O'Sullivan said. "In fact, women burn off more fat than men during exercise, but they don't lose
body fat with exercise as much suggesting women are more efficient fat storers at other times.
The question is why does this paradox exist?"

An obvious answer is that fat storage by women gives an evolutionary benefit, he said. However,
additional research was needed to provide more insights into the role of oestrogen in the
regulation of body fat.

Associate Professor O'Sullivan stressed that while oestrogen's effects on postprandial fatty acid
oxidation provide a mechanism for fat accumulation, the findings do not explain why some
women are obese. Factors contributing to obesity are complex and include both genetic and
environmental factors, he said.
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